Handbook of Physiology, Section 2: The Cardiovascular System, Vol I: The Heart - Hardcover

Hardcover

ISBN 10: 0195098862 ISBN 13: 9780195098860

Publisher: Oxford University Press, 2001

Synopsis

This volume continues the tradition of thoughtful, in-depth examination of critical subjects in the Handbook of Physiology, though the molecular revolution has transformed cardiovascular research from a stable, mature field into one that is exploding with new findings. The 21 chapters were written by outstanding international investigators in the fields of cell structure, muscle contraction and control, and electrophysiology. They cover basic molecular events but highlight the strong relationships to physiological processes that will soon be important in cardiovascular disease. In the discussions of structure, the emphasis is on normal and abnormal growth as well as the dynamic properties of cell communication via gap junctions. Muscle function is explored from actin-myosin molecular interactions to control of intracellular calcium and contraction by its principal transporters. The book shows how cardiac electrophysiology integrates the whole heart from cellular action potentials and conduction to mathematical models. Current concepts of ion channel structure and function and the heterogeneous distribution and expression of these channels are detailed. The heart as a malfunctioning organ is considered in chapters on arrhythmias, ventricular function, and heart failure. The chapters are extensively referenced and focus on the critical questions in basic cardiology for physiologists to address in the future, drawing on the power of molecular studies and the genome map.

About this title

About the Author

Ernest Page, Department of Medicine, University of Chicago. Harry A. Fozzard, Department of Medicine, University of Illinois. R. John Solaro, Department of Physiology and Biophysics, University of Illinois at Chicago College of Medicine.

Review

"Fortunately, the American Physiologic Society has taken on the noble task of publishing compendious "handbooks" that provide a greater wealth of information than most students will ever have the opportunity to enjoy. This text provides detailed chapters that cover the contractile and conductive functions of the heart." --Chest

Edition details

• Publisher: Oxford University Press
• Publication date: 2001
• ISBN 10: 0195098862
• ISBN 13: 9780195098860
• Binding: Hardcover
• Language: English
• Edition number: 1
• Number of pages: 848
• Editor: Page Ernest, Fozzard Harry A., Solaro R. John