Meta-analysis, decision analysis, and cost-effectiveness analysis are the cornerstones of evidence-based medicine. These related quantitative methods have become essential tools in the formulation of clinical and public policy based on the synthesis of evidence. All three methods are taught with increasing frequency in medical schools and schools of public health and in health policy courses at the undergraduate and graduate level. This book is a lucid introduction, and will serve the needs of students taking introductory courses that cover these topics. It will also be useful to clinicians and policymakers who need to understand the quantitative underpinnings of the methods in order to best apply the information that derives from them. The second edition of this popular book adds new material on cumulative meta-analysis as a method to explore heterogeneity. The coverage of cost-effectiveness analysis has been brought into close alignment with recommendations of the U.S. Public Health Panel on Cost-Effectiveness Analysis in Health and Medicine. Many of the examples have been replaced with more current examples, and all of the material has been updated to reflect recent advances in the methods and the emergence of consensus about some previously controversial issues. analysis. These three closely related methods have become even more important for synthesizing research since the first edition was published in 1994. And they have gained legitimacy as tools for guiding health policy.
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Diana B. Petitti is at Southern California Kaiser Permanente Medical Care Program.
"The first edition was very well received and this new work receives my heartiest endorsement....The writing is clear and accessible. Jargon minimal. The text is well-larded with examples....Each chapter has been updated and new material added. The new edition places many recent developments
into context....All in all the book fills an important niche. It is suitable as a text and a reference. Difficult concepts are especially articulately presented. This new edition belongs on the shelf of every aspiring meta-analyst!" --The Epidemiology Monitor
"This book is very well written, easy to understand and apply, with excellent relevant examples. It is the most comprehensive and accessible book in this field....4 STARS." --Doody's Rating
"I have used the text as a primary source in several courses and seminars. Students at various levels of training regularly agrred that it was clearly written and provided numerous relevant examples of the necessary techniques. Often, methodological textbooks provide detailed formulae. In
contrast, this text provides in its numerous examples the actual step-by-step calculations that are needed."--American Journal of Epidemiology
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