Items related to Flow Cytometry for Biotechnology

Flow Cytometry for Biotechnology - Softcover

 
9780195152340: Flow Cytometry for Biotechnology
Softcover
ISBN 10: 0195152344 ISBN 13: 9780195152340
Publisher: Oxford University Press, 2005

Synopsis

Flow cytometry is a sensitive and quantitative platform for the measurement of particle fluorescence. In flow cytometry, the particles in a sample flow in single file through a focused laser beam at rates of hundreds to thousands of particles per second. During the time each particle is in the laser beam, on the order of ten microseconds, one or more fluorescent dyes associated with that particle are excited. The fluorescence emitted from each particle is collected through a microscope objective, spectrally filtered, and detected with photomultiplier tubes.

Flow cytometry is uniquely capable of the precise and quantitative molecular analysis of genomic sequence information, interactions between purified biomolecules and cellular function. Combined with automated sample handling for increased sample throughput, these features make flow cytometry a versatile platform with applications at many stages of drug discovery. Traditionally, the particles studied are cells, especially blood cells; flow cytometry is used extensively in immunology.

This volume shows how flow cytometry is integrated into modern biotechnology, dealing with issues of throughput, content, sensitivity, and high throughput informatics with applications in genomics, proteomics and protein-protein interactions, drug discovery, vaccine development, plant and reproductive biology, pharmacology and toxicology, cell-cell interactions and protein engineering.

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About the Author

Larry Sklar is Regents Professor of Pathology at the University of New Mexico. He is also Director of Basic Research at the University of New Mexico Cancer Research and Treatment Center.

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Publisher
Oxford University Press
Publication date
2005
Language
English
ISBN 10 
0195152344
ISBN 13 
9780195152340
Binding
Paperback
Edition number
1
Number of pages
400
Editor
Sklar Larry A.