Microsatellites: Evolution and Applications

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9780198504078: Microsatellites: Evolution and Applications

Microsatellites are short stretches of repeated DNA that show exceptional variability in humans and most other species. This variability has made microsatellites the genetic marker of choice for numerous applications, including genetic mapping and studies of evolutionary connections between species and populations. This book details the molecular processes which give rise to microsatellite DNA and then describes the wide range of applications in medical genetics, forensics, the study of human evolution, and conservation genetics. Drawing from an international group of researchers, the book presents the theoretical background and the hands-on details for many of the popular analytic methods using microsatellites, including methods for estimating coalescent times, population divergences, and migration.

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About the Author:

David B Goldstein, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS david.goldstein@zoo.ox.ac.uk Christian Schlotterer, Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat Wien, Vienna, Austria christian.schloetterer@vu-wien.ac.at

Review:


"This excellent book makes a strong case for microsatellites...several of the book's editors and contributors have been active in developing these genetic distance measures. This book will provide an excellent introduction and reference for those using tandem repeats in their research." -- The Quarterly Review of Biology, Vol 76, Mar 2001


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Published by Oxford University Press (1999)
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David B. Goldstein (Editor), Christian Schlotterer (Editor)
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Goldstein, David B. (Editor)/ Schlotterer, Christian (Editor)
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