Quantitative Methods in Neuroscience: A Neuroanatomical Approach - Hardcover

Hardcover

ISBN 10: 0198505280 ISBN 13: 9780198505280

Publisher: Oxford University Press, 2004

Synopsis

Stereology is a valuable tool for neuroscientists, allowing them to obtain 3-Dimensional information from 2-Dimensional measurements made on appropriately sampled sections (usually obtained from histological sections or MRI/CT/PET scans). This 3-D information is invaluable in correlating structural/functional relationships in the pursuit of far greater understanding of the function of the central nervous system. However, in carrying out such measurements, often based on limited data sets, there is a risk of experimenter bias. An important feature of modern design based stereology is to be aware of potential sources of bias and eliminate them during the data collection. With many of the major neuroscience journals now insisting that quantitative data be presented, there is a greater need than ever for neuroscientists to understand the theory and practice behind quantitative methods, such as those offered by stereology. Quantitive Methods in Neuroscience is a cookbook of stereological methods written especially for neuroscientists. It provides clear and accessible advice about when and when not to use stereology. Throughout the book, the emphasis is on practical guidance, rather than discussions and formulae. Written by leading scientists in the field of stereology, with a Foreword by D.C. Sterio, the book will be a valuable introduction to these methods for neuroscientists, and all those involved in development of new drug programmes.

About this title

About the Author:

Stephen M Evans is at Hammersmith Imanet, Hammersmith Hospital, London, UK. Ann Marie Janson is in the Department of Neuroscience, Karolinska Institute, Stockholm, Sweden. Jens Randel Nyengaard is at Aarhus University Hospital, Denmark.

Review:

The book is a practical tool for the increasingly large number of neuroscientists who require specific stereological techniques. It is both informative and valuable, in that it suggests appropriate methods and statistical treatments for resolving particular types of stereological problems. * Physiology News, No 57 *

About this edition

• Publisher: Oxford University Press
• Publication date: 2004
• ISBN 10: 0198505280
• ISBN 13: 9780198505280
• Binding: Hardcover
• Edition number: 1
• Number of pages: 332
• Editor: Evans Stephen M., Janson Ann Marie, Nyengaard Jens Randel