Synopsis
Cancer and the mechanisms of its development are receiving increasing research interest. New genes are being isolated almost daily, Fundamental to those studies is the ability to detect mutations. Mutation detection is time consuming and expensive and thus should be undertaken with a thorough knowledge of the alternative methods. This book aims to critically review the field, refer to methodology and protocols, and give illustrative examples as well as put the whole emerging field in context, including ethical considerations.
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About the Author
Richard G. H. Cotton, Mutation Research Centre, St Vincent's Hospital, Victoria.
Review
"Cotton's book is an elegant and balanced account of mutation detection, setting the subject in a truly academic format. Both the historical developments and basic principles are brought together in a clear and very thorough way, and the presentation should empower the reader to `go away and think for himself'. . . .I would recommend this book to anyone with a need to understand mutation detection rather than simply following protocols. . . .An outstanding little book." --Annals of Human Genetics
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Mutation Detection
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Oxford University Press, 1997
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ISBN 10: 0198548893
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Mutation Detection
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ISBN 13: 9780198548898
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