Homeostatic Control of Brain Function - Hardcover

Hardcover

ISBN 10: 0199322295 ISBN 13: 9780199322299

Publisher: Oxford University Press, 2015

Synopsis

Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders.

Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health.

Key Features include
· A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks.
· Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise.
· Incorporation of homeostatic therapies into existing basic and clinical research paradigms.
· Extensive scientific basic and clinical research ranging from molecules to disorders.
· Emerging practical information for improving homeostasis.
· Examples of homeostatic therapies in preventing and delaying dysfunction.

Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

About this title

About the Author

Detlev Boison is the Robert Stone Dow Chair of Neurology; the Director of Neurobiology Research; and the Director of Basic and Translational Research at the Legacy Research Institute

Susan A. Masino is the Vernon Roosa Professor of Applied Science; and a Professor of Neuroscience and Psychology at Trinity College

Review

"Homeostatic Control of Brain Function is a serious resource for scientists at all levels. While outlining detailed mechanisms several dozen experts in the field consider how basic principles of homeostasis influence brain function from molecules to behavior. Accordingly, Homeostatic Control of Brain Function offers insights into why and how to restore homeostasis therapeutically, and perhaps non-pharmacologically. One of the most interesting aspects is up-to-date scientific information underling beneficial and available therapies such as meditation and acupuncture. In sum, Boison and Masino have organized a provocative and forward-looking book as we continue to grapple with new insights and develop therapies for complex and overlapping brain diseases." --Paul Lombroso, MD, Professor and Deputy Chair of Research, Child Study Center and Departments of Psychiatry and Neurobiology, Yale University School of Medicine

"This is an excellent textbook geared for basic scientists studying the metabolic regulation of the brain and methods in which to positively affect metabolism. It is extremely thorough yet very readable, with detailed references and figures. The authors are experts in their fields of study. A must-read for any neuroscientists working in the field of metabolism." --Eric H. W. Kossoff, M.D., Professor, Neurology and Pediatrics, Medical Director, Ketogenic Diet Center, Director, Pediatric Neurology Residency Program, Johns Hopkins Hospital, Baltimore, MD

Edition details

• Publisher: Oxford University Press
• Publication date: 2015
• ISBN 10: 0199322295
• ISBN 13: 9780199322299
• Binding: Hardcover
• Language: English
• Edition number: 1
• Number of pages: 658
• Editor: Boison Detlev, Masino Susan A