Systemic Treatment of Prostate Cancer (Oxford Oncology Library) - Softcover

 
9780199561421: Systemic Treatment of Prostate Cancer (Oxford Oncology Library)
Softcover
ISBN 10: 0199561427 ISBN 13: 9780199561421
Publisher: Oxford University Press, 2010

Synopsis

Prostate cancer is one of the commonest cancers in men in the western world, and the prevalence is rising currently due to improvements in screening and treatment. Serum PSA represents a useful marker of disease. It has frequently a long natural history, creating the opportunities for multiple sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is central to management. Hormone ablation has long been the mainstay of endocrine therapy in this group of patients, though anti-androgens, oestrogens, and corticosteroids can also cause remissions. In recent years effective and well-tolerated chemotherapy regimens have been developed and evaluated. Docetaxel has an established role, and a range of biologically-targeted agents are in development.

The dominant pattern of metastatic spread is to the axial skeleton and most symptomatic care is directed to palliation of bone pain. The role of bisphosphonates remains controversial, but bone-directed isotopes such as Strontium-89 are effective.

Part of the Oxford Oncology Library, this pocketbook summarizes the up-to-date information on the use of systemic therapies in the management of prostate cancer (early stage, metastatic disease, and treatment of "biochemical" recurrence). With contributions from leading oncologists from both Europe and the USA, the book provides a practical guide to the range of endocrine and cytotoxic therapies currently available to clinicians, as well as to other palliative anticancer strategies, and will be valuable to all health professionals involved in the management of patients with prostate cancer.

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About the Author

Alan Horwich is Professor of Oncology at the Royal Marsden Hospital and Institute of Cancer Research, Sutton, UK.

"About this title" may belong to another edition of this title.

Publisher
Oxford University Press
Publication date
2010
Language
English
ISBN 10 
0199561427
ISBN 13 
9780199561421
Binding
Paperback
Edition number
1
Number of pages
104
Editor
Horwich Alan