Extracellular Matrix: A Practical Approach (The Practical Approach Series)

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9780199632213: Extracellular Matrix: A Practical Approach (The Practical Approach Series)
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The importance of the extracellular matrix in maintaining the structural integrity of organisms, in regulating the normal biology of a cell, and in the development and progression of disease, has established this area as a major focus of contemporary research. This book is a timely compendium of the key biochemical, immunological, and molecular biological techniques and approaches currently used to study both extracellular matrix macromolecules and their function in vertebrates. Topics covered include methods for the study of the different genetic types of collagens, the structural glycoproteins (fibronectin, laminin, tenascin, thrombospondin, and SPARC), elastin, glycosaminoglycans, and proteoglycans, for investigating the catabolism of matrix components, for the use of matrix in cell culture, for immunological identification of matrix components in cells and tissues, and for studying the regulation of extracellular matrix gene expression.
Extracellular Matrix: A Practical Approach is a unique source of the latest research methods for all researchers in this subject area. It also represents a valuable information resource for investigators whose major interests lie in related fields.

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About the Author:

M. A. Haralson, Department of Pathology, Vanderbilt University, Nashville, Tennessee. J. R. Hassell, Eye and Ear Institute, University of Pittsburgh, Pennsylvania.

Review:

`valuable ... It is a multi-authored volume in the superb Practical Approach series and comes packed with protocols on every aspects of ECM research. This is the ECM book that has been needed for a long time, and here are essential protocols for any groups with even the slightest interest in
the ECM. I recommend it highly.'
Charles Streuli, University of Manchester, Trends in Cell Biology, (Vol.6), November 1996

`This book sets out to provide the research worker with a comprehensive survey and detailed protocols of the biochemical techniques used for studying the macromolecules of the extracellular matrix. The senior authors of all the chapters are well established in the field of their contribution.
This is a strong recommendation for a book which should become a standard handbook for anyone working in this field, particularly those just entering or wishing to develop new techniques.'
Doreen E. Ashhurst, St George's Hospital Medical School, Cell Biology International, Vol. 20, No. 9, 1996

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9780199632206: Extracellular Matrix: A Practical Approach (Practical Approach Series)

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ISBN 10:  0199632200 ISBN 13:  9780199632206
Publisher: IRL Press, 1996
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Published by Oxford University Press (1996)
ISBN 10: 0199632219 ISBN 13: 9780199632213
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Book Description Oxford University Press, 1996. Condition: New. book. Seller Inventory # M0199632219

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