Human Genetic Disease Analysis: A Practical Approach (Practical Approach Series) - Softcover

Softcover

ISBN 10: 0199633088 ISBN 13: 9780199633081

Publisher: IRL Press, 1993

Synopsis

This book covers all of the commonly used methods for the analysis and diagnosis of human genetic diseases. The chapters describe the analysis of gene mutations as well as the functional organization of genes and chromosomal regions, keeping up-to-date with recent advances in the field. Revisions in this second edition include sections on PCR and FISH. When the first edition of this book was published, prenatal diagnosis based on DNA analysis was performed in two weeks. The advent of PCR has allowed this process to be completed in just a few hours. PCR has had an impact in almost all areas of molecular medicine and thus all the chapters in this new edition have been significantly revised. The development of fluorescence in situ hybridization (FISH) has been important for both genome analysis and diagnosis. This revolutionary new technology is detailed in this volume. The book will be valuable for scientists working in a pure research environment as well as those in service laboratories analyzing different human disease mutations.

About this title

About the Author

K. E. Davies, Head of Molecular Genetics Group, Institute of Molecular Medicine, Oxford.

Edition details

• Publisher: IRL Press
• Publication date: 1993
• Language: English
• ISBN 10: 0199633088
• ISBN 13: 9780199633081
• Binding: Paperback
• Edition number: 2
• Number of pages: 144
• Editor: Davies K. E.