Successful transplantation depends on the minimization of immunological differences between the donor and recipient tissues. These differences are based on polymorphisms of the human major histocompatibility complex and play a major role in determining the acceptance or rejection of allografts during transplantation.
Histocompatibility Testing: A Practical Approach describes methods for the investigation of these polymorphisms at the gene and protein levels and their application to the clinical transplanation of human organs and bone marrow. There is currently no other text available covering these up-to-date serological and molecular techniques in this area of immunogenetics, despite their importance to fundamental research, clinical practice and forensic medicine. This book will therefore be of great interest to researchers in many subject areas, irrespective of whether they are in established laboratories or are entering this field for the first time.
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Philip Dyer, Doctor, Northwest Regional Tissue Typing Laboratory, Manchester. Derek Middleton, Doctor, Tissue Typing Laboratory, City Hospital, Belfast.
'a very useful book and one might safely predict that it will become a standard text on the practical aspects of histocompatibility testing'
J. Andrew Bradley, Western Infirmary, Glasgow, Immunology Today, Vol. 15, No. 6, 1994
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