This book examines DNA-protein interactions from the perspective of the recognition and manipulation of DNA structure. There are a whole series of functionally very important DNA-binding proteins where a central feature of the interaction is the manipulation of DNA structure by bending,
twisting, or wrapping. This book draws together themes from different parts of molecular biology to bring out the importance of DNA structure in the interactions between proteins and DNA.
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David M. J. Lilley, Director, CRC Nucleic Acid Structure Research Group.
"[T]he reader is left with a deep appreciation for the structural and mechanistic possibilities that have emerged from the long co-evolution of DNA and DNA-binding proteins."--Quarterly Review of Biology
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