Platelets: A Practical Approach (The ^APractical Approach Series) - Hardcover

 
9780199635382: Platelets: A Practical Approach (The ^APractical Approach Series)
Hardcover
ISBN 10: 0199635382 ISBN 13: 9780199635382
Publisher: Oxford University Press, 1996

Synopsis

Platelets play an essential role in blood clotting at sites of wound injury, but unwanted activation of platelets in the circulation can give rise to thrombus formation, and is implicated in the onset of stroke, myocardial infarction, and other diseases. Platelets are also one of the major model systems for the study of signal transduction.
This book is a comprehensive and up-to-date practical guide to research on platelets. Each chapter, written by experts in the field, contains detailed protocols, illustrative results, tips and hints for success, and key literature citations. Topics covered include: platelet preparation; monitoring platelet aggregation and secretion; megakaryocyte differentiation; preparation and uses of semipermeabilized platelets; monitoring calcium; identification and characterization of platelet glycoproteins (including the use of PCR); analysis of cell-surface antigens; the role of the cytoskeleton in platelet function; measurement of protein serine/threonine and tyrosine phosphorylation, kinase activity, cyclic nucleotides and G protein function; analysis of phospholipid metabolism, immunocytochemistry and electron microscopy studies; clinical aspects of platelet function; platelet procoagulant activity; and studies of platelet function in species other than man.

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From the Back Cover

Platelets play an essential role in blood clotting at sites of wound injury, but unwanted activation of platelets in the circulation can give rise to thrombus formation, and is implicated in the onset of stroke, myocardial infarction, and other diseases. Platelets are also one of the major model systems for the study of signal transduction. This book is a comprehensive and up-to-date practical guide to research on platelets. Each chapter, written by experts in the field, contains detailed protocols, illustrative results, tips and hints for success, and key literature citations. Topics covered include: platelet preparation; monitoring platelet aggregation and secretion; megakaryocyte differentiation; preparation and uses of semipermeabilized platelets; monitoring calcium; identification and characterization of platelet glycoproteins (including the use of PCR); analysis of cell-surface antigens; the role of the cytoskeleton in platelet function; measurement of protein serine/threonine and tyrosine phosphorylation, kinase activity, cyclic nucleotides and G protein function; analysis of phospholipid metabolism, immunocytochemistry and electron microscopy studies; clinical aspects of platelet function; platelet procoagulant activity; and studies of platelet function in species other than man.

About the Author

Stephen Watson is at University of Oxford. Kalwant Authi is at Thrombosis Research Institute, London.

"About this title" may belong to another edition of this title.

Publisher
Oxford University Press
Publication date
1996
Language
English
ISBN 10 
0199635382
ISBN 13 
9780199635382
Binding
Hardcover
Number of pages
396
Editor
Watson Stephen P., Authi Kalwant S.

Other Popular Editions of the Same Title

9780199635375: Platelets: A Practical Approach

Featured Edition

ISBN 10:  0199635374 ISBN 13:  9780199635375
Publisher: IRL Press, 1996
Softcover