RNA-Protein Interactions: A Practical Approach provides a clear and comprehensive guide to the many experimental procedures used in studying RNA-protein interactions. The approaches covered range from those initially used to detect a novel RNA-protein interaction to various biochemical and genetic approaches, and from in-depth methods for analyzing the structural basis of the interaction to methods for purifying and cloning RNA binding proteins. The volume contains a number of procedures that have not previously been covered in this type of manual, including the production of site-specifically modified RNAs by enzymatic and chemical methods and in vivo screening for novel RNA-protein interactions in yeast and E. coli. This informative book will be a valuable aid to laboratory workers in biochemistry and molecular biology, as well as graduate students and postdoctoral and senior scientists, whose research encompasses this field.
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Dr Christopher W J Smith, Lecturer in Biochemistry, Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Old Addenbrooke's Site, Cambridge CB2 1GA. Tel: 01223 333655 / 333665. Fax: 01223 766002. Email: cwjs1@mole.bio.cam.ac.uk
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