Eukaryotic DNA Replication: A Practical Approach (Practical Approach Series) - Softcover

Softcover

ISBN 10: 019963680X ISBN 13: 9780199636808

Publisher: Oxford University Press, 1999

Synopsis

This volume is a comprehensive practical manual, with each of its eleven chapters describing a key aspect of the methods currently used to investigate DNA replication in eukaryotes. The sequence of the chapters corresponds roughly to the order of events during DNA replication. The first chapters are concerned with initiation, looking at methods to characterize origins of replication and the proteins that interact with them. There then follow chapters describing protocols for the study of the elongation phase and the synthesis of the telomeres. The final chapters provide a more general overview of the study of DNA replication--including its investigation in model systems such as yeast, xenopus and viruses--and looks into methods used to study DNA-protein interactions that could be applied to the study of replication proteins. This exciting new volume provides over 120 tried and tested protocols for the analysis of eukaryotic DNA replication and will be of major interest to a wide variety of molecular and cell biologists, biochemists and medical researchers.

About this title

About the Author

Sue Cotterill is at Marie Curie Research Institute, Oxted, Surrey..

Edition details

• Publisher: Oxford University Press
• Publication date: 1999
• ISBN 10: 019963680X
• ISBN 13: 9780199636808
• Binding: Paperback
• Language: English
• Edition number: 1
• Number of pages: 304
• Editor: Cotterill Sue