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Synopsis
In eukaryotes, DNA is packaged in chromosomes, the structure and number of which provide a great deal of information for many aspects of cellular genetics. This hands-on guide is an up-to-date survey of experimental methods for analyzing chromosome structure, and it includes techniques for vertebrates, Drosophila, yeast, and Xenopus. Organized in a methodical fashion, the book begins with the analysis of chromatin and protein mapping, followed by chapters on whole chromosome structure, then on whole-mount tissues and the analysis of sub-structure in mammals, and concluding with two chapters on the experimental manipulation of chromosome structure. With over 70 protocols, the book will be invaluable for a wide range of researchers in genetics, medicine, and molecular biology.
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About the Author
Dr Wendy A. Bickmore, Cell Genetics Section, MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU. Tel: 0131 332 2471. Fax: 0131 343 2620. Email: wendy@hgu.mrc.ac.uk
Review
"...The book is an essential read for all workers in fields such as molecular biology, genetics and biomedical science whose work involves chromosome analysis." Clinical Laboratory International, September 1999
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- PublisherOxford University Press
- Publication date1999
- ISBN 10 0199636982
- ISBN 13 9780199636983
- BindingPaperback
- LanguageEnglish
- Edition number1
- Number of pages234
- EditorBickmore Wendy A.
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Chromosome Structural Analysis: A Practical Approach
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ISBN 13: 9780199636983
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