Mouse Genetics and Transgenics: A Practical Approach - Softcover

Softcover

ISBN 10: 0199637083 ISBN 13: 9780199637089

Publisher: Oxford University Press, 2000

Synopsis

This unique book integrates knowledge from a wide range of expertise, specifically applied to the mouse and addressed at a wide audience from those new to the field to experts who want an update on the state of the art. Mouse Genetics and Transgenics: A Practical Approach covers all aspects of using the mouse as a genetic model organism: care and husbandry; archiving stocks as frozen embryos or sperm; making new mutations by chemical mutagenesis; transgenesis; gene targeting; mapping mutations and polygenic traits by cytogenetic, genetic, and physical means; and disseminating and researching information via the Internet.

About this title

About the Author

Ian J. Jackson is at MRC Human Genetics Unit, Edinburgh. Cathy Abbott is at Human Genetics Unit, Dept of Medical Sciences, University of Edinburgh.

Review

"An authoritative manual covering all aspects of the production and analysis of mouse mutants and transgenic mice. Initial chapters discuss animal husbandry and cryopreservation methods. This is followed by discussions of various genetic and physical mapping techniques, as well as applications of fluorescence in situ hybridisation (FISH). The final part details the production of transgenic animals from plasmids, BACS and YACS as well as methods of making new mutants by chemical mutagenesis or by targeting ES cells. An excellent resource describing the many databases accessible via the Internet."--Aslib Book Guide

Edition details

• Publisher: Oxford University Press
• Publication date: 2000
• ISBN 10: 0199637083
• ISBN 13: 9780199637089
• Binding: Paperback
• Language: English
• Edition number: 1
• Number of pages: 299
• Editor: Jackson Ian J., Abbott Catherine M.