The Migraine Brain: Imaging Structure and Function - Hardcover

Hardcover

ISBN 10: 019975456X ISBN 13: 9780199754564

Publisher: Oxford University Press, 2012

Synopsis

The Migraine Brain, edited by David Borsook, Arne May, Peter J. Goadsby, and Richard Hargreaves, makes a major contribution to the field, addressing the increasingly sophisticated neuroimaging techniques that have allowed researchers to begin to define functional and anatomical characteristics of migraine and other less-common types of headache. Of particular focus is how imaging is changing the way we understand migraine. This includes changes in function, structure and chemistry of the migraine brain. Included are sections that focus on particular aspects of migraine, for example the migraine aura: those symptoms that cause visual sensitivity (blinding white light), sensory difficulty (loud noises, painful touch, and hot/cold spells), slurred language, and motor dysfunction.

Extensively illustrated throughout, The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.

A collation of the top thinkers in the field and the only book of its kind, The Migraine Brain is necessary reading for neurologists and neuroscientists.

About this title

About the Author

David Borsook, MD, PhD
Director, Pain & Analgesia Imaging Neuroscience (P.A.I.N.) Group
McLean Hospital, Masschussetts General Hospital, and Children's Hospital
Belmont, MA

Arne May, MD, PhD
Institut für Systemische Neurowissenschaften
Zentrum für Experimentelle Medizin
Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany

Peter Goadsby, MD, PhD
Director, UCSF Headache Center
Department of Neurology
University of California, San Francisco
San Francisco, CA

Richard Hargreaves, PhD
Vice President
Worldwide Head of Basic Research
Neuroscience
Merck Research Laboratories
West Point PA

Review

"The Migraine Brain - Imaging Structure and Function reviews the astonishing progress that has been made, based on diverse noninvasive imagining technologies, in visualizing the neural basis of a disorder that, not long ago, was essentially invisible. While some features of migraine could be detected through the neurologic exam, the most salient symptoms, including the headache, were characterized largely through subjective report. Although this multi-authored volume focuses on imaging, it provides a relatively broad outline of migraine, making it useful and interesting for readers beyond the specialist." -- Steven E. Hyman, MD, Broad Institute of Harvard and MIT, Cambridge, MA

"It is a superb summary of the explosion of recent research into the origins and causes of migraine. It highlights the many ways in which the migraine brain is different both during and between individual attacks of headache. It is especially timely because until recently we have been dependent upon clinical observation and static imaging techniques for hints about the origins and process of migraine. Now genetic advances and functional imaging techniques, all elegantly summarized by the world-class expert authors of this book, have put us on a fast track to solving the mysteries of migraine. I view this as essential reading for anyone looking for a synthesis of the exciting progress being made in the dynamic field of migraine research." -- Elizabeth Loder, MD, MPH, The John R. Graham Headache Center, Chief, Division of Headache and Pain, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

"This book is unique in this field. Functional neuroimaging is cutting edge...This book
puts functional neuroimaging of the migraine into clinical context. It can and will be used by readers to learn about the migraine brain and the neuroimaging tools available to study it, to apply this knowledge to help patients, and to inspire further research in this field." -- Amaal Jilani Starling, MD, Mayo Clinic Arizona, Doody's

"The Migraine Brain is an expertly authored and edited compendium of insights into human migraine pathophysiology. The strength of the book is its informative synthesis of an enormous body of literature, accompanied by clinical interpretation by recognized experts in the field. The writing is accessible, and the topics are timely. The Migraine Brain is poised to be a standard reference on the topic of migraine pathophysiology and neuroimaging." -- Jonathan H. Smith, MD, Neurology

"This book is a major contribution to the study of the migraine headache. ... The editors and the authors of the content in this important volume have provided a service of incalcuable value with the information they provide in this milestone work on the migraine brain. They are to be heartily congratulated for their work in researching and writing for this work, and generously sharing their knowledge, experience, and insight." --Biz India

Edition details

• Publisher: Oxford University Press
• Publication date: 2012
• ISBN 10: 019975456X
• ISBN 13: 9780199754564
• Binding: Hardcover
• Language: English
• Edition number: 1
• Number of pages: 400
• Editor: Borsook David, May Arne, Goadsby Peter J., Hargreaves Richard