This text introduces students to the field of psychopharmacology, with special emphasis on the relationships between drugs, their mechanisms of action in the nervous system, and human behavior.
By examining human drug use from historical, societal, and biological perspectives, Grilly provides a rich foundation for understanding drugs affecting the brain and their usage. In addition to describing basic pharmacological principles, Grilly discusses the general factors behind drug tolerance, dependence, and abuse and approaches for dealing with these problems. Pharmacotherapy for the major mental disorders is described from both biochemical and clinical efficacy perspectives. By using the most up-to-date research, and by presenting data in concise, jargon-free prose, the author has created one of the most comprehensive and accessible books on the subject.
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By examining human drug use from historical, societal, and biological perspectives, Grilly: Drugs and Human Behavior, Fifth Edition, provides a rich foundation for understanding drugs affecting the brain. In addition to describing basic pharmacological principles, this text discusses the general factors behind drug tolerance, dependence, and abuse and approaches for dealing with these problems. Pharmacotherapy for the major mental disorders is described from both biochemical and clinical efficacy perspectives. By using the most up-to-date research, and by presenting data in concise, jargon-free prose, the author has created one of the most comprehensive and accessible books on the subject.
Author #1:
After earning his doctorate in experimental psychology at the University of New Mexico in 1971, Dr. Grilly spent the next two years investigating the behavioral effects of cannabinoids after acute and chronic exposure in chimpanzees at Holloman Air Force Base in Alamogordo, New Mexico. He then moved to Cleveland, Ohio, to take a position as a faculty member in the Psychology Department at Cleveland State University, where he spent the remainder of his 38 year career. His research at CSU, primarily with rats, involved investigations of a variety of psychoactive drugs on a variety of behaviors. These included investigating the potential use of signal detection theory in assessing nociception and opiate withdrawal, determining the effects of drugs on attentional processes (e.g., naltrexone, diprenorphine, morphine, barbiturates, amphetamine, cocaine, fluoxetine, nicotine, pemoline) and conditioned avoidance/escape behavior (e.g., clonidine, chlorpromazine, morphine), determining whether the effects of psychostimulants (e.g., cocaine, amphetamine) on sustained attention change with aging, and comparing the effects of very low to very high doses of amphetamine in rats with those shown in humans. He also conducted research with humans investigating the effect of marijuana on visual short term memory and the changes in people’s perceptions of the effects of marijuana on driving.
Author #2: Dr. John Salamone received his bachelor's degree from Rockhurst University in Kansas City, Missouri in 1978. He was a psychology major and biology minor. Dr. Salamone then entered the psychobiology program at Emory University in Atlanta, Georgia, and graduated with a Ph.D. in 1982. For postdoctoral training, Dr. Salamone received a National Science Foundation grant, and studied at Cambridge University in England. Dr. Salamone stayed in England for several more years, working at Merck, Sharpe and Dohme pharmaceutical laboratories. Upon returning to the United States, Dr. Salamone joined the Behavioral Neuroscience department at the University of Pittsburgh in 1986, and joined the Psychology Department at UConn in the fall of 1988. Dr. Salamone is now a Board of Trustees Distinguished Professor; he also is the chair of the Interdisciplinary Program in Neuroscience, and the head of the Behavioral Neuroscience Division of the Psychology Department. Dr. Salamone's research is largely in the fields of behavioral neuroscience and psychopharmacology, with an emphasis on studies related to Parkinson’s disease, depression, motivation, and effort-related decision making. Dr. Salamone has been the research advisor for more than 40 undergraduate honors students at the University of Connecticut. He was inducted as a member of the Connecticut Academy of Arts and Sciences in 2002, and he has received the University of Connecticut Alumni Association Award for Excellence in Teaching. His daughter, Isabella Salamone, is currently an honor student studying biology at the University of Pittsburgh. Dr. Salamone’s hobbies include travel, astronomy, book collecting and cooking.
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