Multiple Sclerosis: Current Status and Strategies for the Future - Hardcover

Institute Of Medicine; Board On Neuroscience And Behavioral Health; Committee On Multiple Sclerosis: Current Status And Strategies For The Future

Hardcover

ISBN 10: 0309072859 ISBN 13: 9780309072854

Publisher: National Academies Press, 2001

Synopsis

Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated.

This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives.

The panel reviews existing knowledge and identifies key research questions, focusing on:

• Research strategies that have the greatest potential to understand the bio- logical mechanisms of recovery and to translate findings into specific strategies for therapy.
• How people adapt to MS and the research needed to improve the lives of people with MS.
• Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others).

The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Table of Contents

• Front Matter
• Executive Summary
• 1 Introduction
• 2 Clinical and Biological Features
• 3 Characteristics and Management of Major Symptoms
• 4 Disease Management and Measurement
• 5 Strategies for Future Research on Disease Mechanisms
• 6 Future Strategies for Therapies
• 7 Building and Supporting the Research Enterprise
• 8 Recommendations
• Appendix A: Committee and Staff Biographies
• Appendix B: List of Expert Consultants
• Appendix C: Workshop Agendas
• Appendix D: Kurtze's Expanded Disability Status Scale
• Appendix E: Drugs Used in the Treatment of MS
• Appendix F: U.S. Social Security Administration's Criteria for Qualifying as Disabled from MS
• Appendix G: Treatments That Have Been Claimed to Be of Benefit in MS
• Index

About this title

About the Author

Janet E. Joy and Richard B. Johnston, Jr., Editors, Committee on Multiple Sclerosis: Current Status and Strategies for the Future, Board on Neuroscience and Behavioral Health

Edition details

• Publisher: National Academies Press
• Publication date: 2001
• ISBN 10: 0309072859
• ISBN 13: 9780309072854
• Binding: Hardcover
• Language: English
• Edition number: 1
• Number of pages: 456
• Editor: Johnston Richard B. Jr., Joy Janet E.