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His thesis, that HIV made the jump from simians to humans via the administration of oral polio vaccine in Africa in the 1950s, is still controversial, but his arguments are powerful, broad, and undeniable--all that is lacking is conclusive proof. Like a good scientist (and, sad to say, unlike any HIV researcher to date), he offers several easy tests of his hypothesis. His tales of brilliant epidemiological deductions, biochemical comparisons, and physiological insights ought to convince the medical establishment that the answer can and should be found, both to help us deal with the current crisis and to keep us from creating new ones of its ilk. In a litigation-weary world, though, it seems that it will take the kind of tireless, impartial research found in The River to show us--and our leaders--that blame should take a back seat to truth when extreme circumstances demand it. --Rob Lightner
Since the early nineties, serious HW researchers have been aware that the most common variant of HIV--human immunodeficiency virus--is the direct descendant of an SIV--simian immunodeficiency virus--carried by African chimpanzees. This still leaves, however, the important and puzzling question of how the virus jumped from chimps to humans, which is all the more intriguing because scientists believe that the SIV has existed harmlessly in chimps for thousands of years, but transferred to humans in the middle of the twentieth century.
At the end of the century, most informed observers believe that only two viable explanations remain for how this might have happened.
Many doctors and scientists think the transfer was "natural," the result of human/chimp encounters--either from the keeping of chimps as pets, or from hunting and skinning chimps for food. That AIDS appeared only recently is due, they argue, to the massive social changes in Africa over the last few decades, including the large migrations that occurred after World War II and the end of European control of Africa.
Others, including Edward Hooper, believe it more likely that the transfer was the result of American and European medical interventions in Africa during the 1950s--and specifically the administration of more than a million doses of an experimental oral polio vaccine, some batches of which may have been manufactured from chimp kidneys. Hooper's extensive investigations and interviews in America, Europe, and Africa lead to some remarkable revelations, which include previously unpublished details about where the vaccines were given and the locations of the earliest traces of HIV and AIDS, as revealed by archival blood and tissue samples. The maps of vaccinations and early AIDS cases are extraordinarily similar.
At the heart of this book is a riveting detective story with frightening implications--including the continued reluctance of the medical and scientific communities to properly investigate the hypothesis that their activities may have inadvertently given birth to the most devastating infectious disease in human history.
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