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Statistics in Human Genetics (Arnold Applications of Statistics Series) - Softcover

 
9780340662410: Statistics in Human Genetics (Arnold Applications of Statistics Series)
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This is one of the first introductions to the sophisticated statistical methods that play a key role in research on human genetics. Topics include the estimation of allele frequencies, the testing for Hardy-Weinberg equilibrium, classical and complex segregation analysis, linkage analysis for Mendelian and complex diseases and quantitative traits, the detection of allelic associations, the estimation of heritability for multifactorial traits and path analysis.

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In human genetic research sophisticated statistical methods are increasingly being used to analyse results. Until now there has been no book to introduce and explain these methods. The methods are based on both biology and statistics and are likely to contribute to major scientific and medical advances in the next century. Topics include the estimation of allele frequencies, the testing for Hardy-Weinberg equilibrium, classical and complex segregation analysis, linkage analysis for Mendelian and complex diseases and quantitative traits, the detection of allelic associations, the estimation of heritability for multifactorial traits and path analysis. An understanding of elementary statistical concepts is assumed, but the objectives, principles and limitations of the methods are discussed in detail.
About the Author:
Pak Sham is at Institute of Psychiatry, London.

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  • PublisherHodder Education Publishers
  • Publication date1997
  • ISBN 10 0340662417
  • ISBN 13 9780340662410
  • BindingPaperback
  • Edition number1
  • Number of pages304

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9780470689288: Statistics in Human Genetics

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  • 9780471194880: Statistics in Human Genetics (Arnold's Applications of Statistics)

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