Bayesian Modeling in Bioinformatics (Chapman & Hall/CRC Biostatistics Series) - Softcover

 
9780367383657: Bayesian Modeling in Bioinformatics (Chapman & Hall/CRC Biostatistics Series)
Softcover
ISBN 10: 0367383659 ISBN 13: 9780367383657
Publisher: Chapman and Hall/CRC, 2019

Synopsis

Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and classification problems in two main high-throughput platforms: microarray gene expression and phylogenic analysis.

The book explores Bayesian techniques and models for detecting differentially expressed genes, classifying differential gene expression, and identifying biomarkers. It develops novel Bayesian nonparametric approaches for bioinformatics problems, measurement error and survival models for cDNA microarrays, a Bayesian hidden Markov modeling approach for CGH array data, Bayesian approaches for phylogenic analysis, sparsity priors for protein-protein interaction predictions, and Bayesian networks for gene expression data. The text also describes applications of mode-oriented stochastic search algorithms, in vitro to in vivo factor profiling, proportional hazards regression using Bayesian kernel machines, and QTL mapping.

Focusing on design, statistical inference, and data analysis from a Bayesian perspective, this volume explores statistical challenges in bioinformatics data analysis and modeling and offers solutions to these problems. It encourages readers to draw on the evolving technologies and promote statistical development in this area of bioinformatics.

"synopsis" may belong to another edition of this title.

About the Author

Dipak K. Dey is a professor and head of the Department of Statistics at the University of Connecticut.

Samiran Ghosh is an assistant professor in the Department of Mathematical Sciences at Indiana University-Purdue University.

Bani K. Mallick is a professor of statistics and director of the Bayesian Bioinformatics Laboratory at Texas A&M University.

"About this title" may belong to another edition of this title.

Publisher
Chapman and Hall/CRC
Publication date
2019
Language
English
ISBN 10 
0367383659
ISBN 13 
9780367383657
Binding
Paperback
Edition number
1
Number of pages
466
Editor
Dey Dipak K., Ghosh Samiran, Mallick Bani K.

Other Popular Editions of the Same Title

9781420070170: Bayesian Modeling in Bioinformatics (Chapman & Hall/CRC Biostatistics Series)

Featured Edition

ISBN 10:  1420070177 ISBN 13:  9781420070170
Publisher: Chapman and Hall/CRC, 2010
Hardcover