Biography of a Germ - Hardcover

Karlen, Arno

Hardcover

ISBN 10: 0375401997 ISBN 13: 9780375401992

Publisher: Pantheon, 2000

Synopsis

This is high drama played out on a very small stage: a microbe's life seen from its own point of view. The bacterium Borrelia burgdorferi (Bb for short) is a tiny, pale spiral, invisible to the naked eye, yet no one could invent a life so ingenious, or one so tied to so many creatures' fates. We know Bb as the germ that causes Lyme disease, but that is just one recent chapter in its age-old struggle to survive. In this brilliant and original book, Arno Karlen takes readers on a fantastic journey through Bb's world--its ancestry and evolution, its day-to-day life, its perilous travels through ticks, mice, and deer, and, finally, its collision with humanity. Its life evokes the vast ecological web in which we and Bb are threads.

Bb is of special interest because it is one of a score of microbes that recently shifted to humans from other species, causing such epidemics as Lyme disease and AIDS. Like its microbial brethren, Bb entered our bodies because we invited it to, by changing our environment and behavior. Its history shows how germs, their hosts, and their shared environment all shape one another.

But Bb is fascinating in its own right, a distinctive member of bacteria's invisible kingdom. And its story is an homage to the researchers who discovered it, mapped its genes, and continue to explore it.

Imaginative, entertaining, and compelling, Biography of a Germ makes science pure pleasure.

About this title

Review

The philosopher Ludwig Wittgenstein might say that if a microbe could talk, we couldn't understand it, but psychoanalyst and science writer Arno Karlen has done his best to listen and translate in Biography of a Germ. This lovely, funny, even endearing portrait of Borrelia burgdorferi (or Bb), the screwy bacterium that causes Lyme disease, would charm even a terminal mysophobe like Howard Hughes. Unfortunately, Karlen has to justify his topic at greater length than do most biographers, but his reasoning is nearly lyrical in its enthusiasm for the microscopic. Following the genealogy of the germ back to our common ancestor (gulp) and beyond, the author finds a freshness in what we too often see as dry taxonomy and genetics. From there, he watches Bb as it makes its way through the circulation superhighways of deer, ticks, and hikers, each a stop on its complex life cycle.

We elbowed our way into Bb's story comparatively recently, ironically hurting ourselves as we renewed our appreciation of and commitment to wilderness areas. As we destroyed, then created habitat for deer, we ended up inviting Bb to run amok in our bodies. Karlen captures the beauty and terror of this bizarre chain of events, providing new insights into our relationship with our environment. Much like its cousins that live harmlessly in our bloodstream, eyelashes, and guts, this tickborne germ will eventually evolve a truce with us to protect its reproduction. Unfortunately for current and future sufferers of Lyme disease, we're quite a few generations away from that happy time. While we're waiting, we can read Biography of a Germ to learn more about our new tenants and why we should care about them. --Rob Lightner

From the Back Cover

"Anro Karlen has written an elegant book that revives an old form: the biographical essay. In the spirit of Dr. Lewis Thomas, he humanizes the story of a germ while entertaining the reader with wonderfully digressive lore on history, biography, the environment, and the way humans imprint themselves on the natural landscape."
-- James Atlas, author of Delmore Schwartz: The Life of an American Poet

About this edition

• Publisher: Pantheon
• Publication date: 2000
• ISBN 10: 0375401997
• ISBN 13: 9780375401992
• Binding: Hardcover
• Edition number: 1
• Number of pages: 192