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Synopsis
Seven years in the making, Altered Fates chronicles the saga of gene therapy, a medical revolution unparalleled in human history.
In the pages of this rich and detailed narrative, whose characters include the field's leading scientists as well as key patients and their families, the Pulitzer Prize-winning authors tell the story of the race to be the first to do gene therapy (a feat almost certain to garner a Nobel Prize and a place in medical history), uncovering the behind-the-scenes machinations and rivalries among the prima-donna researchers at some of the world's leading medical centers, including the National Institutes of Health. They also reveal the details of the initial human experiments in gene transfer and the agonizing decisions faced by the families of the first children to be submitted to the therapy.As Daniel Kevles observed in the New York Times Book Review, "Mr. Lyon and Mr. Gorner are highly knowledgeable about the state of human and medical genetics, and their treatment of both the science and its practitioners is vivid, accessible, and . . . gripping."
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Review
I worked as a programmer for the Human Genome Mapping Library Project with the Howard Hughes Medical Institute several years ago, and have been waiting for thebook that could clearly explain to my friends and relatives what it was that I and the thousands of other folks sequencing human DNA were really up to.
Finally, Lyon and Gorner have written a book that deals with the most profound and compelling implications of this work: gene therapy, or the possibility of bypassing symptoms of diseases by dealing instead with their root genetic. Although this well-researched and comprehensive volume might be a bit much for the casual reader, it is a masterful and colorful work filled with facts, personalities, and politics that would appeal to anyone with a real interest in understanding the history -- and possible futures -- of gene therapy.
About the Author
Jeff Lyon and Peter Gorner, recipients of the Pulitzer Prize for Journalism in 1987 for the stories on which Altered Fates was based, write for the Chicago Tribune. They live in Chicago.
Jeff Lyon and Peter Gorner, recipients of the Pulitzer Prize for Journalism in 1987 for the stories on which Altered Fates was based, write for the Chicago Tribune. They live in Chicago.
"About this title" may belong to another edition of this title.
- PublisherW. W. Norton & Company
- Publication date1996
- ISBN 10 0393315282
- ISBN 13 9780393315288
- BindingPaperback
- Edition number1
- Number of pages636
- Rating
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Altered Fates: The Genetic Re-engineering of Human Life
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W.W. Norton & Co. 1996/10/17 00:00:00.000, 1996
ISBN 10: 0393315282
ISBN 13: 9780393315288
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