Updated and revised, the Third Edition of this standard-setting laboratory reference helps readers to better visualize and analyze human chromosome patterns. It covers the most advanced instrumentation and techniques in the field, features over 200 step-by-step protocols, and increases confidence and skill with advice from contributors from leading laboratories across the country.The Third Edition now includes an expanded FISH chapter / more information and protocols for breakage studies / up-to-the-minute coverage of computer imaging, regulation, the molecular aspects of leukemias, and chromosome spreading / and listings of Internet resources...as well as the latest on cell culture principles / peripheral blood cytogenetic methods / prenatal chromosomal diagnosis / the preparation of chromosome stains / the analysis of cytogenetic abnormalities / the cytogenetic analysis of hematologic malignant diseases / and much more!
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