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Advances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, Smith and Williams’ Introduction to the Principles of Drug Design and Action, Fourth Edition includes the latest information on topics such as gene therapy, computer-aided design, and molecular techniques including proteomics. Using real-world examples that illustrate the principles of drug design, the author explores the discovery of lead compounds and their manipulation in the production of non-toxic, metabolically stable drug candidates that will interact with target receptors in a predicted fashion.
See what’s new in the Fourth Edition:
Fully updates and expands the contents
Coverage of agonists and antagonists of neuro-transmitters
Information on the design of stable peptide-like drugs
The human genome and its impact on drug discovery and development
Advances in therapy and pharmacokinetics
Adopting a from-the-bench-to-the-marketplace approach, the book provides a thorough grounding in rational drug design. It emphasizes principles and elucidates a framework for basic drug design into which current and, more importantly, future drugs will fit.
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- PublisherCRC Press
- Publication date2005
- ISBN 10 0415288770
- ISBN 13 9780415288774
- BindingHardcover
- Edition number4
- Number of pages682
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Smith and Williams' Introduction to the Principles of Drug Design and Action, Fourth Edition
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Book Description Buch. Condition: Neu. Neuware - As knowledge of biological systems and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. Smith and Williams' Introduction to the Principles of Drug Design and Action, Fourth Edition provides the basic principles of rational drug design, including both novel and established approaches. This new edition adopts a from-bench-to-marketplace approach, using real examples where possible. It offers a comprehensive update of the previous edition, particularly with respect to new advances in molecular techniques, biotechnological applications, and computer-aided design. Seller Inventory # 9780415288774
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