Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, functions, mechanisms, and kinetics of enzymes, including their use as disease markers, analytical reagents, and in industrial processes. Subsequent chapters discuss the different types of enzyme inhibitors and the principles involved in developing them into effective drugs. This outstanding text, also valuable as a professional reference, will be useful to all students of pharmacology and medicinal chemistry.
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...value as a focused reference text for graduate students in pharmacology and enzymology. The various subjects are covered clearly and conciselywith adequate referencing, which should allow students to quickly obtain a broad overview of concepts in enzyme inhibitor development, and also to provide a window into more extensive literature in this area.
Journal of Medicinal Chemistry, 2005, volume 48
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