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Cancer Stem Cells and Signaling Pathways ISBN 13: 9780443132124

Cancer Stem Cells and Signaling Pathways - Softcover

 
9780443132124: Cancer Stem Cells and Signaling Pathways

Synopsis

Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression.

  • Presents cancer stem characteristics and their signaling pathways
  • Highlights the use of animal models for cancer research, the use of genetically modified stem cells to deliver antitumor agents, and the significance of stem cell signaling in drug discovery
  • Covers basic and translational research appropriate for scientists and clinicians exploring alternative treatments for various cancers

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About the Authors

Prof. Surajit Pathak, PhD, is currently working as a professor at Chettinad Academy of Research and Education (CARE), Chennai, India (from 2015 to date). He is currently serving as a principal research scientist (2022 June–Dec 2022) at Linkoping University, Linkoping, Sweden. He received his PhD degree from India in 2007 and completed his postdoctoral training (2007–15) from the University of Alabama, United States, the University of Padova, Italy, and the University of Linkoping, Sweden. His current research focuses on “Biomarker discoveries for early detection of colorectal cancer.” He has published more than 100 research articles in peer-reviewed international journals of repute with 2233 citations and 27 H-index. Dr. Pathak has edited Elsevier book “Stem Cells and Aging” in 2021. He is the member of various professional research bodies of India, including the Indian Association of Cancer Research and the Indian Science Congress.

Dr. Antara Banerjee, PhD, is presently working as an associate professor at CARE, Chennai from 2016 to date. After completing her PhD in 2008 from India, Dr. Banerjee pursued her postdoctoral work at the University of Padova, Italy and Linkoping University, Sweden (2009–15). She has published over 95 peer-reviewed research articles in international and national journals with citation index-1408 and H-index 19. The Banerjee’s lab at Chettinad Hospital and Research Institute is now focused on understanding the role of mesenchymal stem cells niche in tissue regeneration and exploring signaling pathways in governing stem cell fate. She is the editor of Elsevier book “Stem Cells and Aging” in 2021. She is the member of various professional research bodies, including the Indian Association of Cancer Research and the Indian Science Congress.

From the Back Cover

Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal disease worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression.

Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement. It also serves as an ideal reference to guide investigators toward further valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation.

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