The Microbiome in Cancer and Autoimmunity - Part B (Volume 395) (International Review of Cell and Molecular Biology, Volume 395) - Hardcover

Hardcover

ISBN 10: 0443317089 ISBN 13: 9780443317088

Publisher: Academic Press, 2025

Synopsis

Microbiome in Cancer and Autoimmunity - Part B, Volume 395 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. Specific chapters cover the Effect of Microbial Dysbiosis on Autoimmune-Associated Inflammation, Gut Microbiota and Systemic Immune Responses in Cancer, The role of microbiome in gastrointestinal cancer, Cancer and Microbiome-Targeted Therapies, Autoimmune disease and Microbiome Targeted Therapies, and the Effect of Diet and Lifestyle on Microbiome Composition.

• Explores the interconnection of Microbiome with Cancer and Autoimmunity
• Covers the complex relationship between the microbiome and the development, progression, and treatment of cancer and autoimmune diseases
• Includes an analysis of the composition, diversity, and functions of microbial communities in influencing cancer and autoimmune conditions
• Discusses how the microbiome influences immune responses, inflammation, and immune tolerance in the context of cancer and autoimmunity

About this title

About the Author

Manisha Singh, PhD, is a trained human and mouse immunologist and during the last 10 years, she has specialized in cancer immunology. The main focus of her work has been to increase the efficacy and understand the molecular mechanisms of various cancer immunotherapies. She is serving as the principal investigator on a 2-year grant ($545,486), having been funded by the US Department of Defense. Dr. Singh's current research is focused on understanding the role of inflammation in immune suppression and resistance to immunotherapy in cancer. Recently, she has submitted the NIH-R01 grant in which she proposed to study the role of IL-1α in immunotherapy induced resistance. She has published 24 peer-reviewed articles and many abstracts in prestigious journals such as Nature Communication, Journal of Immunology, and Journal of Clinical Investigator. Her work has been cited by several prestigious, peer-reviewed, international journals.

From the Back Cover

Microbiome in Cancer and Autoimmunity Part B, offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. From deciphering the molecular mechanisms underlying microbiome-host interactions to unraveling the impact of dysbiosis on disease progression, the book provides a multifaceted analysis of the microbiome's pivotal role in cancer and autoimmunity. With contributions from leading experts in the field, this book serves as a pivotal resource for researchers, clinicians, and healthcare professionals seeking to understand and harness the therapeutic potential of the microbiome in combating cancer and autoimmune conditions.

Edition details

• Publisher: Academic Press
• Publication date: 2025
• Language: English
• ISBN 10: 0443317089
• ISBN 13: 9780443317088
• Binding: Hardcover
• Edition number: 1
• Number of pages: 184
• Editor: Singh Manisha