Aging and the Kidney: Mechanisms, Consequences, and Management Strategies - Softcover

Softcover

ISBN 10: 0443340692 ISBN 13: 9780443340697

Publisher: Academic Press, 2026

Synopsis

Aging and the Kidney: Possible Mechanisms, Consequences, and Management Strategies explores the connection between kidney health and overall well-being with increasing age and longevity. The first part examines histological, structural, physiological, and functional changes that contribute to age-related declines in kidney function. The role of nutrition and proteomics is also discussed. The second part examines the functional decline in elderly patients and includes subparts on impaired quality of life, sleep quality, fall risk, frailty, depression, and sarcopenia. It also considers unique features of hypertension, diabetes, glomerulonephritis, and peripheral vascular disease.

The final part focuses on diagnostic, management, and prevention strategies. Common myths about chronic kidney disease in the elderly are addressed, with particular attention to how a solitary kidney in living donors ages over time. In addition, kidney function and its relationship to neurologic complications, cancers, and cardiovascular disease are explained, along with current treatment approaches, medications, and future directions in the care of elderly patients.

• Covers histological, structural, physiological, and functional changes that lead to decline in kidney function with aging
• Summarizes the most up-to-date research on the kidney’s impact on health and lifespan
• Addresses common myths regarding kidney disease in the elderly
• Provides guidance on diagnostic, management, and prevention strategies in kidney health and disease for the aging patient

About this title

About the Authors

Stephen Z Fadem has been in clinical practice since 1978 and is currently a Clinical Professor of Medicine at Baylor College of Medicine. During his career, he has been involved in both teaching and clinical research. Dr. Fadem’s special interests revolve around how the morbidities associated with advancing kidney disease lead to sarcopenia and frailty. He is currently in the process of planning a large fall prevention research project for dialysis patients. He has participated in 44 clinical trials and currently has 93 publications and book chapters, as well as 38 patient education articles. Dr. Fadem is the recipient of several national awards. He has been recognized as a Top Doctor by Castle-Connolly for several years, has won the Medal of Excellence from AAKP, and the Presidents Lifetime Achievement Award.

Dr. Ahmed Arslan Yousuf Awan is a practicing nephrologist and Assistant Professor, Department of Medicine, Nephrology and Abdominal Transplantation at the Baylor College of Medicine. Dr. Awan is founder and director of Hepatorenal services and site director for Nephrology fellowships at Baylor St. Luke’s Medical Center (BSLMC) and is the elected faculty senator for BSLMC. He is winner of Faculty of the Year award, Leadership award, Excellence in Patient Care award and has received the Houstonia top doctors award for 3 consecutive years. He is the principal investigator for an ongoing study regarding racial disparities in living kidney donation and a member of the KDIGO focused group that recently published updated guidelines regarding management of hepatitis C and CKD. He is on the faculty at Baylor College of Medicine as well as a lead in innovative national and international courses like Nephrology Business Leaders University (NBLU) and the GlomCon Fellowship.

Emaad M Abdel-Rahman, MD, PhD, has been a nephrologist for over three decades specializing in caring for elderly patients with kidney disease, dialysis patients, and patients with acute and chronic kidney diseases. He is director of the UVA Kidney Center Clinic and main hemodialysis unit and leads one of the few home hemodialysis units in the country. Abdel-Rahman has been actively involved in clinical research throughout his career, including both investigator-initiated and industry-related trials. Dr Abdel-Rahman is a recipient of the UVA School of Medicine Dean’s Award for Clinical Excellence and the Department of Medicine Mentoring Excellence award. He has served on the Advisory Geriatric Nephrology Committee and as a member of the steering committee of the Kidney Health Initiative at the American Society of Nephrology. He now serves as interim director of the Nephrology Clinical Research Center within the UVA Division of Nephrology.

From the Back Cover

Aging and the Kidney: Possible Mechanisms, Consequences, and Management Strategies demonstrates the link between kidney health, well-being with increased age, and longevity. The kidney contains both regenerative and terminally differentiated cells, is the crossroad for vascular and inflammatory processes, and exerts control over many of the conditions that characterize chronic, progressive, debilitating disease. Efforts to reduce the decline in glomerular filtration rate can improve the quality of life in the aging population. This book is divided into three significant sections: mechanisms of the aging kidney, clinical consequences, and management and prevention.

The first section delves into histological, structural, physiological, and functional changes leading to decline in kidney function with aging. The impact of nutrition and proteomics are also explained. The second section reviews function decline in elderly patients and includes subsections specific to impaired QOL, sleep quality, fall risk, frailty, depression, and sarcopenia. Unique characteristics of hypertension, diabetes, glomerulonephritis, and peripheral vascular disease are also considered. The final section is devoted to diagnostic, management, and prevention strategies. Common myths regarding chronic kidney disease in the elderly are explored, and special attention is paid to how the solitary kidney in living donors ages over time. Kidney function and its relation to neurologic complications, cancers, cardiovascular disease are presented, and current therapeutic approaches, medications, and future directions in elderly patient care are discussed. This complete work offers an invaluable resource for understanding the impact the aging kidney has on systemic health and offers potential pathways to improve lifespan and well-being in elderly patients.

Edition details

• Publisher: Academic Press
• Publication date: 2026
• Language: English
• ISBN 10: 0443340692
• ISBN 13: 9780443340697
• Binding: Paperback
• Edition number: 1
• Number of pages: 588
• Editor: Fadem MD FACP FASN Stephen, Awan MD FACP Ahmed Arslan Yousuf, Abdel-Rahman MD PhD Emaad