Studies in Natural Products Chemistry: Stereoselective Synthesis (Volume 12) (Studies in Natural Products Chemistry, Volume 12) - Hardcover

Hardcover

ISBN 10: 0444893660 ISBN 13: 9780444893666

Publisher: Elsevier, 1993

Synopsis

Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines.
Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes.
The book can provide useful information to chemists, biologists, students, and researchers.

About this title

About the Author:

Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 930 publications in several fields of organic chemistry.

Review:

...should be considered a required acquisition for research libraries. -- Journal of Medicinal Chemistry

...should be considered a required acquisition for research libraries. -- Journal of Medicinal Chemistry

About this edition

• Publisher: Elsevier
• Publication date: 1993
• ISBN 10: 0444893660
• ISBN 13: 9780444893666
• Binding: Hardcover
• Edition number: 1
• Number of pages: 548
• Editor: Rahman Atta-ur