Cancer Stem Cells: Identification and Targets - Hardcover

Hardcover

ISBN 10: 0470122013 ISBN 13: 9780470122013

Publisher: Wiley-Interscience, 2008

Synopsis

Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology - two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.

About this title

About the Author

Sharmila Bapat, PHD, is a group leader of a small research group at the National Centre for Cell Science at India's University of Pune. She is an author of the first report on the isolation and identification of stem cells in ovarian cancer. Dr. Bapat organizes workshops on topics such as cell line establishment, immortalization of cultured cells, and stem cell protocols. She is also on the board of editors of the recently launched Journal of Ovarian Research.

From the Back Cover

A new frontier in the battle to understand and treat cancer

The identification of cancer stem cells (CSCs) has opened a new avenue for understanding cancer biology and how cancer should be treated. This book, the first dedicated to CSC research, introduces key concepts and discoveries, including:

• Detailed review of the regulatory mechanisms of cancer development and the transformation of CSCs to cancer cells

• Methods of isolation and characterization

• Latest therapeutic advances

• Recent findings in the study of CSCs and the status of current research

• Application of stem cell principles to cancer biology and the challenges of developing combination stem and cancer biology targets for therapeutics

In addition, the book examines specific types of cancers in which CSCs have been identified, including acute leukemias, retinoblastomas, melanomas, and breast, brain, ovarian, and prostate cancers.

Each chapter has been contributed by one or more pioneers in the field and carefully edited to ensure a thorough and uniform approach. Readers gain an insider's view of the authors' laboratories, research methods, and their results. References to the primary literature are provided at the end of each chapter.

As the first book in its field, Cancer Stem Cells is an invaluable repository of information for cancer biologists, stem cell researchers, and clinicians. It will serve as a springboard to understanding the mechanisms of CSCs and their potential for developing new, more effective therapeutics.

From the Inside Flap

A new frontier in the battle to understand and treat cancer

The identification of cancer stem cells (CSCs) has opened a new avenue for understanding cancer biology and how cancer should be treated. This book, the first dedicated to CSC research, introduces key concepts and discoveries, including:

• Detailed review of the regulatory mechanisms of cancer development and the transformation of CSCs to cancer cells

• Methods of isolation and characterization

• Latest therapeutic advances

• Recent findings in the study of CSCs and the status of current research

• Application of stem cell principles to cancer biology and the challenges of developing combination stem and cancer biology targets for therapeutics

In addition, the book examines specific types of cancers in which CSCs have been identified, including acute leukemias, retinoblastomas, melanomas, and breast, brain, ovarian, and prostate cancers.

Each chapter has been contributed by one or more pioneers in the field and carefully edited to ensure a thorough and uniform approach. Readers gain an insider's view of the authors' laboratories, research methods, and their results. References to the primary literature are provided at the end of each chapter.

As the first book in its field, Cancer Stem Cells is an invaluable repository of information for cancer biologists, stem cell researchers, and clinicians. It will serve as a springboard to understanding the mechanisms of CSCs and their potential for developing new, more effective therapeutics.

Edition details

• Publisher: Wiley-Interscience
• Publication date: 2008
• Language: English
• ISBN 10: 0470122013
• ISBN 13: 9780470122013
• Binding: Hardcover
• Edition number: 1
• Number of pages: 272
• Editor: Bapat Sharmila A.