The preeminent book on cancer cytogenetics—now in a valuable new edition
Like its successful predecessors, Cancer Cytogenetics, Third Edition continues to offer authoritative coverage of neoplastic processes at the chromosomal level of genomic organization. Now updated and expanded, this new edition includes detailed information on the most recent advances in the field, incorporating a vast amount of new cytogenetic as well as molecular genetic data from the latest basic and clinical investigations.
Edited by two leading authorities, who are now aided by a panel of internationalexperts, this new edition has been updated to include:
Enhanced coverage of acute and chronic myeloproliferative disorders
The latest findings on acute and chronic lymphoproliferative disorders
Cancer Cytogenetics, Third Edition is a valuable resource for researchers in a wide range of fields, including cytogenetics, medical and molecular genetics, cellular and molecular biology, oncology, and hematology. With its complete coverage of thecytogenetic mechanisms underlying neoplasia, and always with a keen eye on the clinical consequences of the various acquired genetic aberrations, this text will alsobe an indispensable reference for all clinicians involved in the diagnosis and treatment of cancer patients.
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Cancer Cytogenetics
Second Edition
Sverre Heim
Felix Mitelman
Over the past decade, cancer cytogenetics has become widely recognized both as a basic research tool for investigations of tumor biology and a clinical methodology providing vital insights into cancer development and progression. The first edition of this book presented a much-needed conceptual synthesis of this new and rapidly moving field. Now, Cancer Cytogenetics, Second Edition offers a comprehensive, expanded, and up-to-date summary of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations.
Written by two leading experts, Cancer Cytogenetics, Second Edition provides an authoritative description of neoplastic processes at the chromosomal level of genomic organization. The book opens with a summary of cytogenetic methods and terminology, then reviews the key aspects of chromosomal abnormalities in cancer. The remainder of the book is devoted to the karyotypic and molecular genetic characteristics of specific neoplastic disorders and their clinical implications. Included in these sections are eleven entirely new chapters focusing on different types of non-hematologic neoplasms. This extensive expansion from the single-chapter coverage of the first edition was necessitated by a veritable explosion of knowledge in the field of solid tumor cytogenetics.
Specific topics in the Second Edition include:
* Acute and chronic myeloproliferative disorders
* Myelodysplastic syndromes
* Acute and chronic lymphoproliferative disorders
* Malignant lymphomas
* Solid tumors of the respiratory, digestive, and urinary tracts; breast, genital, endocrine, and nervous systems; eye, skin, and bone; and soft tissue
This Second Edition of Cancer Cytogenetics is a valuable resource for researchers in a wide range of fields, including cytogenetics, medical and molecular genetics, cellular and molecular biology, oncology, and hematology. With its complete coverage of the cytogenetic mechanisms underlying neoplasia, this text will also be an indispensable reference for all clinicians involved in the diagnosis and treatment of cancer patients.
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