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Synopsis
The definitive compendium of bioassay procedures and applications
A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models.
Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories.
Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students.
Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which:
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Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer's, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areas
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Covers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity—a particularly significant consideration in the development of safe and tolerable medications
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Highlights clinically relevant methods, ideas, and techniques to support any pharmaceutical researcher
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Suggests guidelines and systems to enhance communication between pharmacologists, chemists, and biologists
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Provides an informative analysis of pharmaceutical bioassay technologies and lab applications
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About the Author
Shiqi Peng is a Professor and Dean at the School of Chemical Biology and Pharmaceutical Sciences of Capital Medical University in Beijing. He is the author of over 220 journal articles, seven books in China, and over 110 Chinese patents.
Ming Zhao is a Professor and Vice Dean at the School of Chemical Biology and Pharmaceutical Sciences of Capital Medical University in Beijing. She is the author of over 120 journal articles, seven books in China, and over 110 Chinese patents.
Review
"In summary, "Pharmaceutical Bioassays" is a useful reference book for research scientists in drug discovery and medicinal chemistry, providing a comprehensive overview of currently available bioassays." (ChemMedChem, 2010)
"About this title" may belong to another edition of this title.
- PublisherWiley
- Publication date2009
- ISBN 10 0470227605
- ISBN 13 9780470227602
- BindingHardcover
- LanguageEnglish
- Edition number1
- Number of pages522
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