This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms.
By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.
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This ground-breaking book draws together leading researchers to review and discuss the most recent advances in the understanding of the molecular genetic pathways of sex determination. Coverage includes the genetics and biochemistry of mammalian sex determination, comparisons with other modes of sex determination, and consideration of the biology of sexual development and of the evolution of sex-determining mechanisms. A major theme running through several chapters is the value of comparative studies of sex-determining mechanisms in different species. In addition, clinical aspects and the genetic analysis of anomalies of human sexual development are also addressed. This exciting book reviews much new and exciting work in this area and identifies promising new research directions.
Derek J. Chadwick and Jamie A. Goode are editors for The Genetics and Biology of Sex Determination and other scientific titles.
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