Protein Engineering: Principles and Practice

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9780471103547: Protein Engineering: Principles and Practice
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PROTEIN ENGINEERING Principles and Practice

Edited by JEFFREY L. CLELAND CHARLES S. CRAIK

Proteins are involved in every aspect of life-structure, motion,catalysis, recognition and regulation. Protein Engineering:Principles and Practice provides a basic framework forunderstanding both proteins and protein engineering. Thiscomprehensive book covers general, yet essential knowledge requiredfor successful protein engineering, including everything from thefundamentals to modifying existing proteins and developing newproteins.

The book begins by introducing the main concepts of proteinengineering, including: understanding protein conformation,comprehending the relationship between protein composition andstructure, and potential methods for predicting a protein'sconformation.

Other major subjects addressed are:
* Using different host cell expression systems to produce specificproteins
* Protein folding
* Structure and function of proteins in relation to drugdesign
* Construction of synthetic metal binding sites in proteins
* Manufacture of tissue plasminogen activator
* Generation of therapeutic antibodies

This broad range of topics provides a solid foundation in proteinengineering and supplies readers with knowledge essential to thedesign and production of proteins.

Of primary interest to protein scientists-both students andresearchers, in academia as well as industry-Protein Engineering isalso extremely useful to chemical engineers, protein chemists,biochemists, and pharmaceutical chemists.

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From the Publisher:

This up-to-the-minute text presents a systematic approach to protein engineering from both fundamental and operational perspectives. Contains a thorough introduction to protein biophysics via chapters dealing with experimental and theoretical determination of protein structure. Discusses each of the various expression systems currently available along with their advantages and limitations. Also includes the difficulty in achieving correctly folded and functional proteins, specific examples of protein engineering use in construction of synthetic metal binding sites, the manufacture of tissue plasminogen and the generation of therapeutic antibodies.

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Published by Wiley-Liss (1996)
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Book Description John Wiley and Sons Ltd, United States, 1996. Hardback. Condition: New. 1. Auflage. Language: English . Brand New Book. PROTEIN ENGINEERING Principles and Practice Edited by JEFFREY L. CLELAND CHARLES S. CRAIK Proteins are involved in every aspect of life-structure, motion, catalysis, recognition and regulation. Protein Engineering: Principles and Practice provides a basic framework for understanding both proteins and protein engineering. This comprehensive book covers general, yet essential knowledge required for successful protein engineering, including everything from the fundamentals to modifying existing proteins and developing new proteins. The book begins by introducing the main concepts of protein engineering, including: understanding protein conformation, comprehending the relationship between protein composition and structure, and potential methods for predicting a protein s conformation. Other major subjects addressed are: Using different host cell expression systems to produce specific proteins Protein folding Structure and function of proteins in relation to drug design Construction of synthetic metal binding sites in proteins Manufacture of tissue plasminogen activator Generation of therapeutic antibodies This broad range of topics provides a solid foundation in protein engineering and supplies readers with knowledge essential to the design and production of proteins. Of primary interest to protein scientists-both students and researchers, in academia as well as industry-Protein Engineering is also extremely useful to chemical engineers, protein chemists, biochemists, and pharmaceutical chemists. Seller Inventory # AAH9780471103547

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Published by John Wiley and Sons Ltd, United States (1996)
ISBN 10: 0471103543 ISBN 13: 9780471103547
New Hardcover First Edition Quantity Available: 1
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Book Description John Wiley and Sons Ltd, United States, 1996. Hardback. Condition: New. 1. Auflage. Language: English . Brand New Book. PROTEIN ENGINEERING Principles and Practice Edited by JEFFREY L. CLELAND CHARLES S. CRAIK Proteins are involved in every aspect of life-structure, motion, catalysis, recognition and regulation. Protein Engineering: Principles and Practice provides a basic framework for understanding both proteins and protein engineering. This comprehensive book covers general, yet essential knowledge required for successful protein engineering, including everything from the fundamentals to modifying existing proteins and developing new proteins. The book begins by introducing the main concepts of protein engineering, including: understanding protein conformation, comprehending the relationship between protein composition and structure, and potential methods for predicting a protein s conformation. Other major subjects addressed are: Using different host cell expression systems to produce specific proteins Protein folding Structure and function of proteins in relation to drug design Construction of synthetic metal binding sites in proteins Manufacture of tissue plasminogen activator Generation of therapeutic antibodies This broad range of topics provides a solid foundation in protein engineering and supplies readers with knowledge essential to the design and production of proteins. Of primary interest to protein scientists-both students and researchers, in academia as well as industry-Protein Engineering is also extremely useful to chemical engineers, protein chemists, biochemists, and pharmaceutical chemists. Seller Inventory # AAH9780471103547

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Cleland, Jeffrey L.
Published by Wileyand#8211;Blackwell (1996)
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Book Description Wileyand#8211;Blackwell, 1996. HRD. Condition: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Seller Inventory # FW-9780471103547

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Cleland, Jeffrey L. (Editor)/ Craik, Charles S. (Editor)
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Book Description Wiley-Liss, 1996. Hardcover. Condition: Brand New. 1st edition. 544 pages. 10.50x7.50x1.25 inches. In Stock. Seller Inventory # __0471103543

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