Combinatorial Chemistry: Synthesis and Application - Hardcover

 
9780471126874: Combinatorial Chemistry: Synthesis and Application
Hardcover
ISBN 10: 047112687X ISBN 13: 9780471126874
Publisher: Wiley-Interscience, 1997

Synopsis

The new time-saving revolution in drug discovery.

Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation.

Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development. Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes:
* Concepts and terms of combinatorial chemistry
* Polymer-supported synthesis of organic compounds
* Macro beads as microreactors
* Solid-phase methods in combinatorial chemistry
* Encoded combinatorial libraries, including Rf-encoding of synthesis beads
* Strategies for combinatorial libraries of oligosaccharides
* Combinatorial libraries of peptides, proteins, and antibodies using biological systems.

While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.

"synopsis" may belong to another edition of this title.

About the Author

Stephen R. Wilson is Professor of Chemistry at New York University. He is also founder and President of Sphere Biosystems, Inc., in New Jersey, a biotech company based on fullerene combinatorial chemistry technology.

Anthony W. Czarnik is Senior Director of Chemistry at IRORI Quantum Microchemistry in La Jolla, California, and formerly Director of BioOrganic Chemistry at Parke-Davis Pharmaceutical Research.

From the Back Cover

The new time-saving revolution in drug discovery.

Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation.

Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development. Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes:
* Concepts and terms of combinatorial chemistry
* Polymer-supported synthesis of organic compounds
* Macro beads as microreactors
* Solid-phase methods in combinatorial chemistry
* Encoded combinatorial libraries, including Rf-encoding of synthesis beads
* Strategies for combinatorial libraries of oligosaccharides
* Combinatorial libraries of peptides, proteins, and antibodies using biological systems.

While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.

From the Inside Flap

The new time-saving revolution in drug discovery.

Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation.

Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development. Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes:
* Concepts and terms of combinatorial chemistry
* Polymer-supported synthesis of organic compounds
* Macro beads as microreactors
* Solid-phase methods in combinatorial chemistry
* Encoded combinatorial libraries, including Rf-encoding of synthesis beads
* Strategies for combinatorial libraries of oligosaccharides
* Combinatorial libraries of peptides, proteins, and antibodies using biological systems.

While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.

"About this title" may belong to another edition of this title.

Publisher
Wiley-Interscience
Publication date
1997
Language
English
ISBN 10 
047112687X
ISBN 13 
9780471126874
Binding
Hardcover
Edition number
1
Number of pages
288
Editor
Wilson Stephen R., Czarnik Anthony W.

Other Popular Editions of the Same Title

9788126541041: Wiley India Combinatorial Chemistry: Synthesis and Application (O.P. Price $173.00)

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ISBN 10:  8126541040 ISBN 13:  9788126541041
Publisher: Wiley India
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