The Dose Makes the Poison: A Plain-Language Guide to Toxicology, 2nd Edition - Softcover

Ottoboni, M. Alice

Softcover

ISBN 10: 0471288373 ISBN 13: 9780471288374

Publisher: John Wiley & Sons Inc, 1997

Synopsis

The Dose Makes the Poison A Plain-Language Guide to Toxicology Second Edition M. Alice Ottoboni Increasing media coverage of reports on the effects of chemicals, new recognition within government and industry of the need to protect against exposure, and other current issues are elevating the public's concern about the health effects of synthetic chemicals in our environment. Unfortunately, much of this concern is based more on sensational news reports and half-truths than on scientific facts. This second edition of a widely read and highly acclaimed work reviews and explains the facts of chemical dangers in a clear and understandable manner. It objectively discusses the factors determining whether chemicals in our air, food, and water are harmful or harmless, and puts the dose - response relationship of chemicals in proper perspective. Effects of chemicals encountered at home and at work are presented in layman's language to assure understanding without having to turn to other references. Thoughtful discussions of controversial issues help you to understand news media reports on toxicology, avoid the half-truths that lead to "poison paranoia," and make informed judgments about our use and control of chemicals. Extensively revised, the second edition is also reorganized to expedite access to specific information. All experimental and analytical methods are in one section, and references to the origins of toxicology and regulation of chemicals are in another separate section to improve ease of reading. In addition, coverage of subjects such as public distrust of science, epidemiology, reproductive toxicology, and risk have been expanded to provide a better understanding of the relationship of toxicology to current environmental problems. All aspects of exposure and its effects are reviewed, including
* How chemicals cause harm--toxicity, sensitization, corrosiveness, irritation, radioactivity, and other properties
* Routes of exposure--skin, inhalation, oral, and combinations
* Factors that influence degree of toxicity--species, age, sex, nutrition, state of health, presence of other chemicals, adaptation, and possibly, light
* Chemicals that cause cancer and birth defects
Chapters on toxicity of chemicals address no-effect levels and thresholds, margins of safety, and bioaccumulation. You'll see how the effects of chemicals are studied and how health problems are traced to environmental causes. Also clarified are differences between actual risk and perceived risk of various chemicals. With the media presenting us daily with new findings on chemical risks, this book provides a welcome "antidote" to the confusion. The Dose Makes the Poison is an easy-to-read review of toxicology that has become "required reading" for scientists and managers throughout industry; public health officials; environmental scientists; industrial hygienists; hazardous waste workers ; and anyone who wishes to improve his or her understanding of toxic chemicals without taking the time to go back to school.

About this title

About the Author

About the Author M. ALICE OTTOBONI, Ph.D., lectures, writes, and consults in the field of toxicology. As Staff Toxicologist with the California State Department of Public Health for over twenty years, she originated, designed, and performed numerous toxicological studies of environmental factors of importance to public health. She is the author of the first edition of The Dose Makes the Poison, in addition to numerous papers published in scientific journals. She is listed in Who's Who of American Women, American Men and Women of Science, and in the Dictionary of International Biography. Dr. Ottoboni earned the Ph.D. in comparative biochemistry at the University of California, Davis.

Review

Alice Ottoboni's second edition of "The Dose Makes The Poison", a "plain language guide to toxicology" is must reading for every industrial hygienist, client, employer, and daily contact of the industrial hygienist. Ottoboni takes us on a well organized tour of toxicology in layman's terms. The distinctions between poison, toxicity and hazard are sharply drawn. Thorough explanations of factors that influence toxicity are included. Cogent examples using using everday items like foods which contain toxic materials (caffeine in coffee, solanine in potatoes, or ethanol in vodka) make clear the ability of the body to handle divided doses. Dr. Ottoboni helps us understand the difference between the trauma we cause from a needless fear of a chemical than the trauma we cause when we permit exposure to toxicologically significant amounts of that chemical. -- Dr. H. L. Kusnetz, past president of the American Industrial Hygiene Association (AIHA) and the American Academy of Industrial Hygiene (AAIH)

Edition details

• Publisher: John Wiley & Sons Inc
• Publication date: 1997
• ISBN 10: 0471288373
• ISBN 13: 9780471288374
• Binding: Paperback
• Language: English
• Edition number: 2
• Number of pages: 256