Biomedical Chemistry: Applying Chemical Principles to the Understanding and Treatment of Disease

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9780471326335: Biomedical Chemistry: Applying Chemical Principles to the Understanding and Treatment of Disease
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How basic chemical ideas help advance the understanding andtreatment of disease Biomedical Chemistry presents clear, concisecoverage of the application of chemistry to drug discovery anddetermination of disease etiology, highlighting its role in theexplosive growth of biotechnology and molecular biology. Throughexpert contributions from leading researchers in diverse fields,the book provides readers with an understanding of how fundamentalchemical concepts are used in the development of novel approachesto the major problems in medicine today. The authors explain boththe science and reasoning underlying each experimental approach,exploring cutting-edge developments in AIDS, cancer, alcoholism,Parkinson's disease, trypanosomiasis, emphysema, and malaria.Contemporary research problems discussed include:
* Mechanism-based drug discovery
* Design of new antitumor and antiviral agents
* Targeting tumors using magnetic drug delivery
* Antisense and antigene agents
Easily accessible to anyone with a solid undergraduate backgroundin chemistry, Biomedical Chemistry is an excellent resource forresearchers in health-related fields as well as anyone seeking anoverview of frontier topics in medicinal chemistry, organicchemistry, and biochemistry.

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About the Author:

PAUL F. TORRENCE, PhD, is Professor and Chair of Chemistry at Northern Arizona University in Flagstaff, and formerly Chief of the Biomedical Chemistry Section, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, and Director of the Foundation for Advanced Education in the Sciences Graduate School at the National Institutes of Health. Dr. Torrence is widely recognized for his contributions to medicinal chemistry and has published more than 190 scientific papers and patents.

Review:

"Explains the application of chemistry to drug discovery anddetermination of disease etiology...provides an understanding ofhow fundamental chemical concepts are used..." (SciTech BookNews, March 2001)

"At what must be considered a modest price, this book is warmlyrecommended as a good overall survey of the field to chemists andbiochemists working in biomedical or related areas. It will alsoappeal to teachers of organic chemistry as a source book ofmedically relevant example..." (Journal of the American ChemicalSociety, Vol. 123, No. 30, 2001)

"In an age of disposable artifacts and useless gadgets, this isa book to pick up frequently, read slowly, assimilate, and aboveall enjoy." (Pharmaceutical Research, Vol. 18, No. 9,September 2001)

"A fascinating book...one of the best summaries of the newapproach that I have seen." (Chemistry & Industry, 19November, 2001)

"...an essential handbook..." (Journal of NaturalProducts, 2003)

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