Biomedical Chemistry: Applying Chemical Principles to the Understanding and Treatment of Disease - Hardcover

Hardcover

ISBN 10: 047132633X ISBN 13: 9780471326335

Publisher: Wiley-Interscience, 2000

Synopsis

How basic chemical ideas help advance the understanding and treatment of disease Biomedical Chemistry presents clear, concise coverage of the application of chemistry to drug discovery and determination of disease etiology, highlighting its role in the explosive growth of biotechnology and molecular biology. Through expert contributions from leading researchers in diverse fields, the book provides readers with an understanding of how fundamental chemical concepts are used in the development of novel approaches to the major problems in medicine today. The authors explain both the science and reasoning underlying each experimental approach, exploring cutting-edge developments in AIDS, cancer, alcoholism, Parkinson's disease, trypanosomiasis, emphysema, and malaria. Contemporary research problems discussed include:
* Mechanism-based drug discovery
* Design of new antitumor and antiviral agents
* Targeting tumors using magnetic drug delivery
* Antisense and antigene agents
Easily accessible to anyone with a solid undergraduate background in chemistry, Biomedical Chemistry is an excellent resource for researchers in health-related fields as well as anyone seeking an overview of frontier topics in medicinal chemistry, organic chemistry, and biochemistry.

About this title

About the Author:

PAUL F. TORRENCE, PhD, is Professor and Chair of Chemistry at Northern Arizona University in Flagstaff, and formerly Chief of the Biomedical Chemistry Section, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, and Director of the Foundation for Advanced Education in the Sciences Graduate School at the National Institutes of Health. Dr. Torrence is widely recognized for his contributions to medicinal chemistry and has published more than 190 scientific papers and patents.

Review:

"Explains the application of chemistry to drug discovery and determination of disease etiology...provides an understanding of how fundamental chemical concepts are used..." (SciTech Book News, March 2001)

"At what must be considered a modest price, this book is warmly recommended as a good overall survey of the field to chemists and biochemists working in biomedical or related areas. It will also appeal to teachers of organic chemistry as a source book of medically relevant example..." (Journal of the American Chemical Society, Vol. 123, No. 30, 2001)

"In an age of disposable artifacts and useless gadgets, this is a book to pick up frequently, read slowly, assimilate, and above all enjoy." (Pharmaceutical Research, Vol. 18, No. 9, September 2001)

"A fascinating book...one of the best summaries of the new approach that I have seen." (Chemistry & Industry, 19 November, 2001)

"...an essential handbook..." (Journal of Natural Products, 2003)

About this edition

• Publisher: Wiley-Interscience
• Publication date: 2000
• ISBN 10: 047132633X
• ISBN 13: 9780471326335
• Binding: Hardcover
• Edition number: 1
• Number of pages: 432
• Editor: Torrence Paul F.