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Cancer Cytogenetics ISBN 13: 9780471638162

Cancer Cytogenetics - Hardcover

 
9780471638162: Cancer Cytogenetics
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Offers extensive discussions covering the entire field of chromosomal aberrations: abnormalities found in human tumor cells, the pathogenic mechanisms they reveal, and the clinical implications of these changes. Emphasizes aspects of cancer cytogenetics which are of direct clinical significance to oncologists. Examines various specific chromosome abnormalities associated with different neoplasms and looks at cytogenetic abnormalities accrued during disease progression. Begins with a brief introduction to the field which includes an informative summary of cytogenetic nomenclature and methology. Goes on to examine the characteristic cytogenetic abnormalities found in different neoplastic diseases, such as lymphoblastic and chronic myeloid leukemia. Also includes examples of the molecular consequences of cytogenetic aberrations in conjunction with descriptions of these abnormalities.

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From the Back Cover:
Cancer Cytogenetics

Second Edition

Sverre Heim

Felix Mitelman

Over the past decade, cancer cytogenetics has become widely recognized both as a basic research tool for investigations of tumor biology and a clinical methodology providing vital insights into cancer development and progression. The first edition of this book presented a much-needed conceptual synthesis of this new and rapidly moving field. Now, Cancer Cytogenetics, Second Edition offers a comprehensive, expanded, and up-to-date summary of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations.

Written by two leading experts, Cancer Cytogenetics, Second Edition provides an authoritative description of neoplastic processes at the chromosomal level of genomic organization. The book opens with a summary of cytogenetic methods and terminology, then reviews the key aspects of chromosomal abnormalities in cancer. The remainder of the book is devoted to the karyotypic and molecular genetic characteristics of specific neoplastic disorders and their clinical implications. Included in these sections are eleven entirely new chapters focusing on different types of non-hematologic neoplasms. This extensive expansion from the single-chapter coverage of the first edition was necessitated by a veritable explosion of knowledge in the field of solid tumor cytogenetics.

Specific topics in the Second Edition include:
* Acute and chronic myeloproliferative disorders
* Myelodysplastic syndromes
* Acute and chronic lymphoproliferative disorders
* Malignant lymphomas
* Solid tumors of the respiratory, digestive, and urinary tracts; breast, genital, endocrine, and nervous systems; eye, skin, and bone; and soft tissue

This Second Edition of Cancer Cytogenetics is a valuable resource for researchers in a wide range of fields, including cytogenetics, medical and molecular genetics, cellular and molecular biology, oncology, and hematology. With its complete coverage of the cytogenetic mechanisms underlying neoplasia, this text will also be an indispensable reference for all clinicians involved in the diagnosis and treatment of cancer patients.

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Other Popular Editions of the Same Title

9780470181799: Cancer Cytogenetics: Chromosomal and Molecular Genetic Abberations of Tumor Cells

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ISBN 10:  0470181796 ISBN 13:  9780470181799
Publisher: Wiley-Blackwell, 2009
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    Wiley-..., 1995
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  • 9780845142394: Cancer cytogenetics

    A.R. Liss, 1987
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Published by Wiley-Liss (1987)
ISBN 10: 0471638161 ISBN 13: 9780471638162
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