Using the Chinese hamster cell as a model system, this volume examines a wide variety of genetic systems. Each chapter addresses the rationale for development of these systems, the details of mutant isolation and analysis, the major conclusions derived from these genetic studies, and the molecular basis for the expression of mutant phenotypes. Comparison is made with genetic analysis developed in non-Chinese hamster cell systems so that the reader has an overview of the state of knowledge for each genetic locus.
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