Published 100 years after Emil Fischer first proposed the lock-and-key principle, this volume provides a complete review of the subject to date and offers suggestions for futher research. The major impact of the lock-and-key principle on the chemical, biomedical and materials sciences is discussed by leaders in the field, with chapters dedicated to molecular recognition, nucleic acid and protein chemistry, crystallography and the development of Emil Fischer's initial ideas. The Lock-and-Key Principle is the most up-to-date review of progress in supramolecular chemistry and the lock-and-key principle and will become the essential guide to the past, present and future of this remarkable principle.
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Perspectives in Supramolecular Chemistry Editorial Board Founding Editor J.-M. Lehn, Université Louis Pasteur, Strasbourg, France Editors J.-P. Behr, Université Louis Pasteur, Strasbourg, France G. R. Desiraju, University of Hyderabad, Hyderabad, India A. D. Hamilton, University of Pittsburgh, Pittsburgh, USA T. Kunitake, Kyushu University, Fukuoka, Japan D.N. Reinhoudt, University of Twente, AE Enschede, The Netherlands J.-P. Sauvage, Université Louis Pasteur, Strasbourg, France
Perspectives in Supramolecular Chemistry — Volume 1 The Lock and Key Principle The State of the Art—100 Years On Edited by Jean-Paul Behr Université Louis Pasteur, Strasbourg, France Contributors Ian M. Bell, The Scripps Research Institute, La Jolla, USA S. J. Benkovic, Pennsylvania State University, Pennsylvania, USA F. Cramer, Max-Plank Institut für Experimentelle Medizin, Göttingen, Germany D. Hilvert, The Scripps Research Institute, La Jolla, USA E. A. Horovitz, The Weizmann Institute of Science, Rehovot, Israel E. Katchalski-Katzir, The Weizmann Institute of Science, Rehovot, Israel H. Kuhn, formerly Max-Planck-Institut für biophysikalische Chemie, Göttingen M. Lahav, The Weizmann Institute of Science, Rehovot, Israel D. Lancet, The Weizmann Institute of Science, Rehovot, Israel J.-M. Lehn, Université Louis Pasteur, Strasbourg, France L. Leiserowitz The Weizmann Institute of Science, Rehovot, Israel D. B. Smithrud, Pennsylvania State University, Pennsylvania, USA V. V. Vlassov, Institute of Bioorganic Chemistry, Novosibirsk, Russia
Forthcoming titles in Perspectives in Supramolecular Chemistry Volume 2: Supramolecular Chemistry in the Solid State Edited by Gautam Desiraju, University of Hyderabad, India
This volume will concentrate on the crystalline structures of supramolecules. Contributions will include Crystals as Supramolecules, Molecular Shape Considerations in Crystals Engineering, The Intermolecular Implication of Protein Function and Molecular Engineering of Crystals by Electrostatic Templating. Volume 3: Supramolecular Control of Structure and Reactivity Edited by Andrew Hamilton, Massachusetts Institute of Technology, Cambridge, USA This volume will deal with the catalytic properties of supramolecules, particularly in biological systems. Topics covered include Design of Self-Replicating Molecules, Synthetic Control of Oligonucleotide Structure, Micellar Catalysis and A Survey of Recent Developments in Supramolecular Catalysis.
Perspectives in Supramolecular Chemistry will relate recent developments and new exciting approaches in supramolecular chemistry. In supramolecular chemistry, our aim is to understand the molecular chemistry beyond the covalent bond-- the series will concentrate on goal-orientated supramolecular chemistry. Perspectives in Supramolecular Chemistry will reflect research which develops supramolecular structures with specific new properties, such as recognition, transport and simulation of biosystems or new materials. The series will cover all areas from theoretical and modelling aspects through organic and inorganic chemistry and biochemistry to materials, solid-state and polymer sciences, reflecting the many and varied applications of supramolecular structures in modern chemistry. The Lock and Key Principle The State of the Art-- 100 Years on Edited by Jean-Paul Behr Published 100 years after Emil Fischer first proposed the lock-and-key principle, this volume provides a complete review of the subject to date and offers suggestions for further research. The major impact of the lock-and-key principle on the chemical, biomedical and materials sciences is discussed by leaders in the field, with chapters dedicated to molecular recognition, nucleic acid and protein chemistry, crystallography and the development of Emil Fischer's initial ideas. The Lock-and-Key Principle is the most up-to-date review of progress in supramolecular chemistry and the lock-and-key principle, and will become the essential guide to the past, present and future of this remarkable idea. The interdisciplinary nature of this topic is highlighted in The Lock-and-Key Principle ensuring that this volume isessential reading for chemists, molecular biologists, biochemists and materials scientists working in the areas of molecular recognition, enzymology, immunology, protein and nucleic acid chemistry, crystallography, bioinorganic and bioorganic chemistry and supramolecular chemistry.
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