Potassium Channels And Their Modulators: From Synthesis To Clinical Experience - Hardcover

Evans, John M

Hardcover

ISBN 10: 0748405577 ISBN 13: 9780748405572

Publisher: Taylor and Francis, 1996

Synopsis

Potassium ions K+ ions are vital in physiological processes, particularly with regard to the cardiovascular system. Modulators influence the channels through which these ions flow and the research into modulator drugs of these channels is the subject of rapidly-advancing research. This work is intended to be of use as a tool for those working in the pharmaceutical industry. Early chapters concentrate on the synthesis and structure-activity relationships of potassium channel modulators. These are followed by discussion on the application of these drugs to different target organs, such as the cardiovascular system and the airways. The book concludes with a broad overview of clinical experience and future prospects.; The authors show how potassium channel activators and potassium channel blockers each have a role to play as therapeutic agents for many disorders, including asthma and respiratory tract disorders, diseases of the central nervous system such as epilepsy, and vascular diseases such as angina, peripheral vascular disease and high blood pressure. This book should therefore also be of interest to those researching into this wide range of diseases.

About this title

About the Author

Euripidis Loukis is Assistant Professor of Information and Decision Support Systems at the University of Aegean, Greece, and also teaches at the National Academy of Public Administration. He has previously been Information Systems Advisor at the Ministry to the Presidency of Government, and Representative of Greece at the European Union in several e-government/e-participation committees. Ann Macintosh is Professor of Digital Governance and Co-director of the Centre of Digital Citizenship at the University of Leeds, UK. She has acted as a specialist advisor for the OECD, the UN and the Commonwealth Secretariat,. In 2009 she was awarded an Honorary Doctorate from Orebro University, Sweden, for recognition of her work in eParticipation. Yannis Charalabidis is Assistant Professor of e-Governance Information Systems at the University of Aegean, Greece and also leads eGovernment & eBusiness Research in the Decision Support Systems Laboratory of National Technical University of Athens. In 2008 he received the Best Paper Award in the Electronic Government - Electronic Participation International Conference.

Edition details

• Publisher: Taylor and Francis
• Publication date: 1996
• Language: English
• ISBN 10: 0748405577
• ISBN 13: 9780748405572
• Binding: Hardcover
• Number of pages: 424