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Synopsis
James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined from a minimum of experimental data and on theoretical argu ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. "It has not escaped our notice," Francis wrote, "that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material." By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act ". . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before" and, moreover, " ...
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The Polymerase Chain Reaction (Volume 0)
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The Polymerase Chain Reaction
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Paperback. Condition: Fair. James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc- ture we had divined from a minimum of experimental data and on theoretical argu- ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. It has not escaped our notice, Francis wrote, that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material. By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act . . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before and, moreover, . Seller Inventory # 00102084420
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The Polymerase Chain Reaction
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Paperback. Condition: Good. James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc- ture we had divined from a minimum of experimental data and on theoretical argu- ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. It has not escaped our notice, Francis wrote, that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material. By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act . . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before and, moreover, . Seller Inventory # 00105132371
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The Polymerase Chain Reaction
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Paperback. Condition: Good. James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc- ture we had divined from a minimum of experimental data and on theoretical argu- ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. It has not escaped our notice, Francis wrote, that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material. By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act . . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before and, moreover, . Seller Inventory # CIN0817637508G
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The Polymerase Chain Reaction
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Paperback. Condition: Fair. James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc- ture we had divined from a minimum of experimental data and on theoretical argu- ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. It has not escaped our notice, Francis wrote, that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material. By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act . . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before and, moreover, . Seller Inventory # CIN0817637508A
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The Polymerase Chain Reaction
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The Polymerase Chain Reaction (Volume 0)
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THE POLYMERASE CHAIN REACTION
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The Polymerase Chain Reaction
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Birkhäuser Boston Mrz 1994, 1994
ISBN 10: 0817637508
ISBN 13: 9780817637507
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined from a minimum of experimental data and on theoretical argu ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. 'It has not escaped our notice,' Francis wrote, 'that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material.' By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act '. . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before' and, moreover, ' . 484 pp. Englisch. Seller Inventory # 9780817637507
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The Polymerase Chain Reaction
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule w. Seller Inventory # 5975485
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