Library Design, Search Methods, and Applications of Fragment-Based Drug Design (ACS Symposium Series)

0 avg rating
( 0 ratings by Goodreads )
 
9780841224926: Library Design, Search Methods, and Applications of Fragment-Based Drug Design (ACS Symposium Series)

Fragment based ligand design is a promising technique for identifying novel lead compounds for drug discovery. Fragment based discovery involves identifying small low molecular weight compounds with low affinity to the target to use as the foundation for growing and linking to create high affinity lead compounds with high selectivity. Fragment based discovery has facilitated the incorporation of greater chemical diversity in libraries for more efficient novel lead identification This book discusses computational methods for fragment library design, computational docking ranking and screening of fragments and computational methods for linking and growing fragments to yield lead compounds.

"synopsis" may belong to another edition of this title.

About the Author:


Dr. Rachelle J. Bienstock, received her undergraduate degree in Chemical Engineering from The Cooper Union in New York City and her Ph.D. in Chemistry from The University of Michigan in Ann Arbor, Michigan. Following postdoctoral studies at the University of Texas Southwestern Medical Center (Dallas), involving NMR and molecular modeling of constrained peptide analogs and peptidomimetics, she joined The National Institute of Environmental Health Sciences, (NIEHS), Research Triangle Park, NC, as a molecular modeler and computational chemist. Her main research interests are protein structure and protein complex prediction methodologies, computational and structure based ligand design methods and protein-protein and protein-ligand docking studies.

"About this title" may belong to another edition of this title.

Buy New View Book
List Price: US$ 160.00
US$ 98.20

Convert Currency

Shipping: US$ 3.99
Within U.S.A.

Destination, Rates & Speeds

Add to Basket

Top Search Results from the AbeBooks Marketplace

1.

Rachelle Bienstock (Editor)
Published by American Chemical Society (2012)
ISBN 10: 0841224927 ISBN 13: 9780841224926
New Hardcover Quantity Available: 1
Seller:
Ergodebooks
(RICHMOND, TX, U.S.A.)
Rating
[?]

Book Description American Chemical Society, 2012. Hardcover. Book Condition: New. Bookseller Inventory # DADAX0841224927

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 98.20
Convert Currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, Rates & Speeds

2.

Published by American Chemical Society (2012)
ISBN 10: 0841224927 ISBN 13: 9780841224926
New Hardcover First Edition Quantity Available: 1
Seller:
Irish Booksellers
(Rumford, ME, U.S.A.)
Rating
[?]

Book Description American Chemical Society, 2012. Hardcover. Book Condition: New. book. Bookseller Inventory # M0841224927

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 118.03
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds

3.

Published by American Chemical Society (2012)
ISBN 10: 0841224927 ISBN 13: 9780841224926
New Hardcover Quantity Available: 1
Seller:
Revaluation Books
(Exeter, United Kingdom)
Rating
[?]

Book Description American Chemical Society, 2012. Hardcover. Book Condition: Brand New. 1st edition. 216 pages. 9.00x6.10x0.90 inches. In Stock. Bookseller Inventory # 0841224927

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 186.73
Convert Currency

Add to Basket

Shipping: US$ 7.97
From United Kingdom to U.S.A.
Destination, Rates & Speeds