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Synopsis
Because enzyme-catalyzed reactions exhibit higher enantioselectivity, regioselectivity, substrate specificity, and stability, they require mild conditions to react while prompting higher reaction efficiency and product yields. Biocatalysis in the Pharmaceutical and Biotechnology Industries examines the use of catalysts to produce fine chemicals and chiral intermediates in a variety of pharmaceutical, agrochemical, and other biotechnological applications.
Written by internationally recognized scientists in biocatalysis, the authors analyze the synthesis of chiral intermediates for over 60 brand-name pharmaceuticals for a wide range of drug therapies and treatments. From starting material to product, the chapters offer detailed mechanisms that show chiral intermediates and other by-products for each reaction―including hydrolytic, acylation, halogenation, esterification, dehalogenation, oxidation-reduction, oxygenation, hydroxylation, deamination, transamination, and C–C, C–N, C–O bonds formation. Cutting-edge topics include advanced methodologies for gene shuffling and directed evolution of biocatalysts; the custom engineering of enzymes; the use of microbial cells and isolated biocatalysts; the use of renewable starting materials; and generating novel molecules by combinatorial biocatalysis and high-throughput screening.
Focusing on industrial applications, the book also considers factors such as bulk processes, instrumentation, solvent selection, and techniques for catalyst immobilization, reusability, and yield optimization throughout. Biocatalysis in the Pharmaceutical and Biotechnology Industries showcases the practical advantages and methodologies for using biocatalysts to develop and produce chiral pharmaceuticals and fine chemicals.
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About the Author
Patel, Ramesh N.
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Biocatalysis in the Pharmaceutical and Biotechnology Industries
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Hardcover. Condition: Fine. 0849337321. Unread Pictorial board hardcover, from closed pharmaceutical company library. Lending record shows this book has never been borrowed. 893 pages, index, illustrated with charts, tables and diagrams. Enzyme-catalyzed reactions exhibit higher enantioselectivity, regioselectivity, substrate specificity, and stability, they require mild conditions to react while prompting higher reaction efficiency and product yields. Examines the use of catalysts to produce fine chemicals and chiral intermediates in a variety of pharmaceutical, agrochemical, and other biotechnological applications. Cutting-edge topics include advanced methodologies for gene shuffling and directed evolution of biocatalysts; custom engineering of enzymes; the use of microbial cells and isolated biocatalysts; the use of renewable starting materials; and generating novel molecules by combinatorial biocatalysis and high-throughput screening. Considers factors such as bulk processes, instrumentation, solvent selection, and techniques for catalyst immobilization, reusability, and yield optimization throughout. Explains practical advantages and methodologies for using biocatalysts to develop and produce chiral pharmaceuticals and fine chemicals. Contents clean, tight and bright. Seller Inventory # 026894
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Biocatalysis in the Pharmaceutical and Biotechnology Industries
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Condition: very_good. Gently read. May have name of previous ownership, or ex-library edition. Binding tight; spine straight and smooth, with no creasing; covers clean and crisp. Minimal signs of handling or shelving. 100% GUARANTEE! Shipped with delivery confirmation, if you're not satisfied with purchase please return item! Ships USPS Media Mail. Seller Inventory # OTV.0849337321.VG
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Biocatalysis in the Pharmaceutical and Biotechnology Industries
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Condition: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions. Seller Inventory # Z1-T-022-01772
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Biocatalysis in the Pharmaceutical and Biotechnology Industries
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Biocatalysis in the Pharmaceutical and Biotechnology Industries
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BIOCATALYSIS IN THE PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES (HB 2007)
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BIOCATALYSIS IN THE PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES (HB 2007)
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Biocatalysis in the Pharmaceutical and Biotechnology Industries
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BIOCATALYSIS IN THE PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES (HB 2007)
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BIOCATALYSIS IN THE PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRIES
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