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Synopsis
Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers.
Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.
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From the Back Cover
The term 'signal transduction' denotes the biochemical sequence of reactions that occurs as a cell responds to external stimuli. It comprises the initial step of hormone binding to a receptor, activation of transmembrane events, triggering of cytoplasmic reaction cascades, and generation of new proteins through which the appropriate cell responses (morphologic change, growth, differentiation, and cell-cell interactions) can take place.
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Signal Transduction in Leukocytes: G Protein-Related and Other Pathways
Seller: The Book Bin, Salem, OR, U.S.A.
Seller rating 5 out of 5 stars
Hardcover. Condition: As New. Liker New, light shelf wear. Year 1996. 383pp. > Language: English | > Size: 8vo - over 7 3/4 in - 9 3/4 in Tall | > Media/Binding: Hardcover |. Seller Inventory # CORV-BBC-0K50467
Quantity: 1 available