Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA

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9780849392337: Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA
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The analysis of DNA sequence polymorphisms and mutations is of central importance in understanding biological systems. This book is devoted to the experimental analysis of DNA and presents easy-to-follow protocols. Various techniques from the simple to the highly complex are detailed in this volume, providing a wide spectrum of available methods and practical advice. The methods are described in terms of:

  • History and background
  • Principles and theory
  • Equipment and reagents
  • Protocols
  • Troubleshooting
  • Applications
  • Improvements
  • Results
  • Comparisons with other methods
  • Future prospects and developments
    This is an essential manual for researchers working in human, animal, or plant molecular genetics and is particularly valuable for hospital and commercial laboratories.
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