Structural Biology of Membrane Proteins (RSC Biomolecular Sciences, Volume 4) - Hardcover

Hardcover

ISBN 10: 0854043616 ISBN 13: 9780854043613

Publisher: Royal Society of Chemistry, 2006

Synopsis

In the last few years there have been many exciting and innovative developments in the field of membrane protein structure and this trend is set to continue. Structural Biology of Membrane Proteins is a new monograph covering a wide range of topics with contributions from leading experts in the field. The book is split into three sections: the first discusses topics such as expression, purification and crystallisation; the second covers characterisation techniques and the final section looks at new protein structures. The book will hence have wide appeal to researchers working in and around the field and provide an up-to-date reference source. Introductory sections to each topic are accompanied by more detailed discussions for the more experienced biochemist. Detailed descriptions of experimental methods are included to demonstrate practical approaches to membrane protein structure projects. The book also offers an up-to-date reference source in addition to descriptions of new and emerging developments, including state-of-the-art techniques for solving membrane protein structures. Structural Biology of Membrane Proteins encompasses both basic introductions and detailed descriptions of themes and should appeal to a wide range of biochemical scientists, both experienced and beginner.

About this title

About the Author

Reinhard Grisshammer has studied the structure and function of G-protein-coupled receptors during the past 15 years, establishing a bacterial expression system for production of these eukaryotic membrane proteins, and developing a large-scale purification procedure for obtaining milligram quantities of homogeneous, functional receptors for structural studies.

Susan Buchanan has studied bacterial outer membrane proteins that transport iron and other small or large molecules during the past 10 years, developing methods for high level expression, purification, and crystallization, followed by structure determination by X-ray crystallography.

Review

...an up-to-date account of the state of the art in this field....a snapshot of the state of the art in the structural biology of membrane proteins.This book fills a gap and can serve both the membrane-protein researcher who is interested in other methods as well as other scientists who wish to get a general overview of the current state of membrane-protein structural biology.A very well presented and informative account of structural biology of membrane proteins. (ChemBioChem, 2007, 8, 145-147 (Clemens Glaubitz))

About this edition

• Publisher: Royal Society of Chemistry
• Publication date: 2006
• ISBN 10: 0854043616
• ISBN 13: 9780854043613
• Binding: Hardcover
• Edition number: 1
• Number of pages: 414
• Editor: Grisshammer Reinhard, Buchanan Susan K